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Found 147 clinical trials
Danish Cardiovascular Screening Trial II (DANCAVAS-II)

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.

cardiovascular disease
  • 13 views
  • 06 Feb, 2022
  • 4 locations
PET Imaging of Inflammation and Lipid Lowering Study

While 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging has been used as an early marker of drug efficacy in numerous clinical cardiovascular drug trials, as a glucose analog, its signal in the vasculature lacks inflammatory cell-specificity. Moreover, high background 18F-FDG signals from the myocardium often preclude coronary artery imaging, despite …

cholesterol level
LDL Cholesterol
glucose analog
stroke
18f-fdg
  • 0 views
  • 30 Aug, 2021
  • 1 location
Role of A2A Receptor in Hypercholesterolemic Patients

Hypercholesterolemia promotes chronic inflammation, endothelial dysfunction, atherosclerosis and is a major risk factor for cardiovascular disease (CVD). Treatment with lipid-lowering drugs

cardiovascular disease
Accepts healthy volunteers
hmg-coa reductase inhibitors
cholesterol measurement
ezetimibe
  • 0 views
  • 15 Nov, 2021
  • 1 location
Effect of Oleactiv® on LDL Oxidability (e-POL)

human. The main hypothesis of the present study is that phenolic compounds from Oleactiv® may improve LDL oxidability in volunteers with moderate hypercholesterolemia after 3 weeks of consumption.

cholesterol measurement
a 12
Accepts healthy volunteers
LDL Cholesterol
atherosclerosis
  • 0 views
  • 26 Mar, 2022
Investigating the Dose Response of an Almond-enriched Diet on Optimizing HDL-C in a Population With Hypercholesterolemia

This study will determine the quantity of almonds (1.5 oz or 2.5 oz) consumed as a snack that will provide optimal increases in HDL-C levels.

hypercholesterolemia
  • 0 views
  • 26 Mar, 2022
  • 1 location
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol

This study will comprise a randomized controlled, counter-balanced, cross-over trial to evaluate the independent effects of a high cholesterol (high egg), low saturated fat diet and a high

cholesterol level
cholesterol measurement
blood lipids
Accepts healthy volunteers
  • 0 views
  • 17 Mar, 2022
Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH) (ID-FH)

The overall goal of this study is to promote awareness of Familial Hypercholesterolemia (FH). The investigators aim to enroll patients with suspected FH into the study and will randomize them to

cholesterol level
Accepts healthy volunteers
  • 0 views
  • 08 Mar, 2022
  • 2 locations
Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention (SMALL LIPIDS)

Combination antiretroviral therapy (ART, HIV medications) dramatically increases the expected lifespan of HIV (Human Immunodeficiency Virus)infected patients; yet, the risks for cardiovascular disease (CVD), such as heart attacks and stroke, are increased in this population. This increased risk may be linked to persistent inflammation and activation of the immune system. …

body mass index
antiretroviral agents
hiv-1 rna measurement
LDL Cholesterol
HIV Vaccine
  • 11 views
  • 14 May, 2022
  • 1 location
Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. (FH-Diet)

The investigators will first conduct a fully controlled dietary randomized crossover trial (RCT) including 72 adults with HeFH to investigate the impact of a diet low in red and processed meats and high in plant foods, reflecting Canada's Food Guide, in place of a standard North-American diet on LDL-cholesterol (LDL-C) …

cholesterol measurement
hypercholesterolemia
cholesterol level
cardiovascular disease
Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Study to Evaluate the Efficacy and Safety in Patients With Primary Hypercholesterolemia

To Evaluate the Efficacy and Safety of Combination Therapy of AGT and AGZ Versus Monotherapy of AGT in Patients With Primary Hypercholesterolemia.

  • 0 views
  • 23 Mar, 2022
  • 1 location