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Found 137 clinical trials
The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

with homozygous familial hypercholesterolemia (hoFH). Patients with this very rare disorder have very high blood levels of cholesterol from birth due to the inheritance of an abnormal gene from each

  • 16 views
  • 15 Oct, 2022
  • 1 location
Subclinical Atherosclerosis in Patients With Familial Hypercholesterolemia Treated With Evolocumab®

changes in lipid profile, oxidation markers and subclinical atherosclerosis in patients with familial hypercholesterolemia (FH) during 12 weeks of treatment with a PCSK-9 inhibitor, Evolocumab.

cholesterol level
atherosclerosis
evolocumab
  • 0 views
  • 01 Mar, 2022
  • 1 location
Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia (FH-FEMINA) (FH-FEMINA)

The study aims to investigate the effects of breastfeeding on lipid profile and cardiovascular risk markers in women with familial hypercholesterolemia (FH). Women with FH who are pregnant or

statin
  • 0 views
  • 24 Oct, 2022
  • 1 location
LOWER: Lomitapide Observational Worldwide Evaluation Registry

This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.

  • 0 views
  • 27 Jan, 2021
  • 47 locations
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing

participants. The investigators will be recruiting women aged 35-65 years with no known heart disease or heart disease risk factors like high blood pressure or high cholesterol. Participants will

Accepts healthy volunteers
  • 103 views
  • 23 Jan, 2022
  • 1 location
Retrograde Approach in Ambulatory Practice

cardiovascular pathologies, such as age, smoking, hypertension, diabetes and hypercholesterolemia, are closely linked to Obliterative arterial disease of the lower limbs. Over the past 20 years, the

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Blood And Clot Thrombectomy Registry And Collaboration (BACTRAC)

This is a prospective open enrollment registry to evaluate arterial blood and thrombus removed during the standard thrombectomy procedure, which will then be used for the purposes of identifying biological markers, inflammatory cell infiltrates, and biological states in large vessel occlusive stroke in the human condition. The primary objectives are …

  • 13 views
  • 19 Jun, 2022
  • 1 location
Study of Awareness and Detection of Familial Hypercholesterolemia (CASCADE-FH)

between The Familial Hypercholesterolemia Foundation, the Duke Clinical Research Institute, lipid specialists, cardiologists, primary care providers, quality improvement personnel, and patients, all

familial hypercholesterolemia
cholesterol measurement
hypercholesterolemia
  • 39 views
  • 10 May, 2022
  • 1 location
A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting (VICTORION-Implement)

This is a multicenter, non-randomized, non-interventional three-cohort study with prospective collection of primary data of treatment with newly initiated oral Lipid lowering treatment on top of a statin (Oral LLT cohort), newly initiated Inclisiran (Inclisiran cohort) and newly initiated Inclisiran on top of lipid apheresis (Apheresis plus Inclisiran cohort) in …

ezetimibe
pcsk9
hmg-coa reductase inhibitors
  • 0 views
  • 24 Oct, 2022
  • 58 locations
Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada (FHCanada)

Familial hypercholesterolemia (FH) is the most frequent genetic lipoprotein disorder associated with premature CAD. In Canada, the burden of disease is estimated to be approximately 83,500

therapeutic agents
premature
cholesterol level
hypercholesterolemia
biopharmaceutical
  • 29 views
  • 24 Jan, 2022
  • 1 location