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Found 27 clinical trials
Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

This study will see if the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures is better than a surgeon's detection alone. It compares risk-benefits and outcomes in PTx patients where NIRAF detection with PTeye for …

parathyroidectomy
parathyroid
primary hyperparathyroidism
parathyroid surgery
parathyroid hormones
  • 0 views
  • 21 Mar, 2022
  • 1 location
Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up

General consensus and contemporary guidelines, recommend surgery for primary hyperparathyroidism (pHPT)for all patients below the age of 50, for patients with pronounced hypercalcemia and for

bone mineral density
parathyroid
primary hyperparathyroidism
parathyroid hormones
osteoporosis
  • 276 views
  • 12 Mar, 2022
  • 1 location
Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy (NIRAF)

This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during parathyroidectomy (PTx) procedures. It compares risk-benefits and outcomes in PTx patients where NIRAF …

parathyroidectomy
parathyroid
primary hyperparathyroidism
parathyroid hormones
hyperparathyroidism
  • 50 views
  • 19 Apr, 2022
  • 1 location
A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. (MegaMOST)

>Absence of symptoms and signs (including worsening of laboratory values; e.g., new or worsening hypercalcemia) that indicate unequivocal progression of disease, No decline in ECOG

  • 0 views
  • 05 Jun, 2022
  • 5 locations
Protocol Active Surveillance Small Renal Masses (SRMs)

syndrome (fever, cachexia, hypercalcemia, polycythemia, ranulocytosis) 6. willingness expressed by the patient to undergo surgery or ablative operation In the presence of at least one of the aforementioned

metastasis
renal neoplasm
nephrectomy
hypercalcemia
  • 3 views
  • 27 Feb, 2022
  • 1 location
Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss of ambulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, and inevitably premature death of affected young men in their late twenties. DMD is the most common fatal genetic disorder diagnosed in …

ace inhibitor
heart failure
angiotensin
aldosterone
ejection fraction
  • 8 views
  • 14 Jul, 2022
  • 10 locations
Early Feasibility Study - Transcatheter Atrial Shunt System (ALt FLOW US)

The purpose of this study is to evaluate initial clinical safety, device functionality and effectiveness of the Edwards Transcatheter Atrial Shunt System.

medical therapy
b-type natriuretic peptide
heart failure
  • 15 views
  • 26 Mar, 2022
  • 10 locations
Denosumab for Smoldering Multiple Myeloma

This study will assess the safety and tolerability of denosumab in smoldering multiple myeloma subjects as well to see if denosumab can reduce subjects' risk of getting multiple myeloma.

hysterectomy
bone marrow plasma cells
calcium
renal failure
bone lesions
  • 0 views
  • 04 Feb, 2022
  • 1 location
The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )

The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relapses) and the quality of life, including levels of physical activity, in children diagnosed Crohn's disease (CD).

cholecalciferol
crohn's disease
tumor necrosis factor
tumor necrosis factor alpha
vitamin
  • 139 views
  • 26 Jan, 2021
  • 7 locations
The Tether - Vertebral Body Tethering System Post Approval Study

This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.

  • 0 views
  • 27 Jan, 2021
  • 1 location