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Found 19 clinical trials
Outcomes of AVS With or Without ACTH Stimulation in PA

To compare the effect of different procedures of AVS(with or without ACTH stimulation) on the long-term outcomes of patients with PA

  • 0 views
  • 03 Sep, 2021
  • 1 location
Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas (FABULAS)

High blood pressure (hypertension) causes strokes and heart attacks. While most patients need long-term treatment with pills, some have a cause which can be removed, curing the hypertension. The commonest curable cause is a benign nodule in one of the hormone glands, the adrenals. About one in 20 patients have …

radiofrequency ablation
hypertension
heart attacks
aldosterone
renin
  • 37 views
  • 03 Mar, 2022
  • 2 locations
Calcium Channel Blockade in Primary Aldosteronism

Primary aldosteronism is a common cause of hypertension. Recent evidence suggests that many patients with bilateral idiopathic hyperaldosteronism harbor gain-of-function somatic mutations in

hyperaldosteronism
aldosterone
calcium channel
renin
adrenal venous sampling
  • 0 views
  • 16 Dec, 2021
  • 1 location
Prevalence of Primary Aldosteronism Among Hypertensive Patients With Atrial Arythmia

Atrial arrhythmia is the most frequent cardiac arrhythmia. It is a source of significant morbidity. Hypertension is a major risk factor for atrial arrhythmias. Primary hyperaldosteronism

hypertension
diagnostic procedure
aldosterone
arrhythmia
atrial arrhythmia
  • 0 views
  • 08 Aug, 2021
  • 2 locations
Effects of Adrenal Artery Ablation and Spironolactone in Patients With Primary Aldosteronism

partial removal of adrenals can reduce aldosterone level, lower blood pressure and restore potassium metabolism balance. In patients with primary hyperaldosteronism, the level of aldosterone

captopril
electrolytes
congenital adrenal hyperplasia
hyperaldosteronism
heart failure
  • 0 views
  • 24 Jan, 2021
  • 1 location
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)

This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection. Depending on the anatomical structures/organs to be visualized during CT examinations, different scanning protocols are performed …

  • 0 views
  • 10 Mar, 2021
  • 1 location
Application of 68Ga-Pentixafor PET/CT in Primary Aldosteronism and Pre-postoperative of SAAE

Primary aldosteronism is the most common cause of secondary hypertension. The two main types of primary aldosteronism are aldosteronoma(30%) and adrenal hyperplasia(60%). The gold standard that determines the diagnosis and treatment strategy of primary aldosteronism is adrenal vein sampling(AVS), but the success rate is only about 80%. Using CXCR4 as …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Establishment of Aldosterone and Renin Reference Range (ARR)

Elevated aldosterone levels were also shown to contribute to the excess morbidity and mortality. Literature shows aldosterone and renin levels differ between ethnicity and gender. There is no established reference intervals for these two hormone levels in Asian community. We aim to establish reference intervals for plasma aldosterone and direct …

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Primary Aldosteronism in Western Norway

In this study the investigators aim to identify and include consecutively patients with primary aldosteronism (PA) diagnosed in the Western and Mid-parts of Norway, to describe the characteristics of these patients, to explore the cardiac effects of PA before and after specific treatment, and to identify long-term outcomes after treatment. …

Accepts healthy volunteers
  • 5 views
  • 11 May, 2022
  • 1 location
Chongqing Primary Aldosteronism Study

We intends to conduct a series of original clinical research about PA, and establish a large cohort of PA and essential hypertension patients with long-term follow-up of cardiovascular events, renal end points etc. We will establish a large sample of blood, urine, adrenal tissue of the subjects, and the genomics,metabonomics, …

hypertension
hyperaldosteronism
  • 0 views
  • 25 Feb, 2022
  • 1 location