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Found 89 clinical trials
Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19

COVID-19 patients with a severely symptomatic progression with development of an Acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 need prolonged intensive care treatment involving pharmacological immobilization, sedation and mechanical ventilation, leaving them at a very high risk for developing Critical illness myopathy (CIM). CIM is associated with increased mortality …

acute respiratory distress syndrome
critical illness
SARS
covid-19
acute respiratory distress
  • 0 views
  • 15 Jul, 2021
  • 1 location
PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs

PHENOTYPE is an investigator-led, observational cohort study which aims to explore the long-term outcomes of patients with COVID-19 infection and to identify potential risk factors and biomarkers that can prognosticate disease severity and trajectory.

covid-19
  • 0 views
  • 18 Aug, 2021
  • 1 location
Endothelial Function Inflammation and Organ Dysfunction in COVID-19

COVID-19 is a rapidly evolving pandemic with approximately 5% of all patients which require intensive care unit admission. In critically ill patients infected with COVID-19, approximately 15% had severe shock requiring medications to increase blood pressure. It appears that blood vessel tone is altered and microcirculation is not well regulated …

  • 0 views
  • 16 Aug, 2021
  • 1 location
A Study to Explore the Role of Gut Flora in COVID-19 Infection

This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.

Accepts healthy volunteers
SARS
covid-19
  • 0 views
  • 05 Mar, 2022
  • 1 location
COVID-19 Immune Repertoire Sequencing (IMSEQ)

This concerns a single-center prospective interventional cohort study. Laboratory-confirmed COVID-19 patients will be asked to donate blood at at least two different timepoints. This will allow us to investigate T and B cell evolutions during the course of infection and recovery. The expected duration of the study is four months …

SARS
covid-19
  • 0 views
  • 24 Apr, 2022
  • 1 location
In-vitro Diagnostic Test to Predict COVID-19 Mortality and Disease Severity

The COVID-19 Androgen Sensitivity Test is a non-invasive In-Vitro Diagnostic device that utilizes Next Generation Sequencing Technology (NGS). The results of the test are used by a physician to assess the risk of developing severe symptoms following COVID-19 infection, The COVID-19 Androgen Sensitivity Test requires a health care professional to …

SARS
androgens
covid-19
  • 847 views
  • 24 Mar, 2022
  • 1 location
Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

This study aims to find out whether the use of angiotensin II, which is a drug to raise blood pressure has been approved by European Medical Agency in August 2019, as an add-on medication to increase blood pressure in patients with COVID-19, acute severe lung injury, inflammation and severe shock, …

coronavirus infection
norepinephrine
covid-19
acute respiratory distress
cytokines
  • 0 views
  • 15 Aug, 2021
  • 1 location
Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury

The aim is to describe the epidemiology and determine the independent risk factors for mortality and acute organ injury in AKI and to assess the impact of different treatment strategies on survival. This will allow the development of prevention strategies and design of appropriately powered intervention studies.

critical illness
renal injury
covid-19
  • 27 views
  • 15 Aug, 2021
  • 1 location
PRediction Of Flares In Lupus With autoantibodiEs and Chemokines (PROFILE)

Rationale: Systemic lupus erythematosus (SLE) is a chronic relapsing-remitting autoimmune disease with a wide range of clinical manifestations affecting several organs. Although the management of lupus patients has improved in the last years, accurate models for predicting disease progression are lacking. Objective: To prospectively evaluate the predictive value of a …

lupus
  • 0 views
  • 03 Jun, 2022
  • 1 location