Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 90 clinical trials
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

The trial will develop and validate a platform for quantitative assessment of antiviral effects in low-risk patients with high viral burdens and uncomplicated COVID-19. In this randomised open label, controlled, group sequential adaptive platform trial, we will assess the performance of three distinct types of intervention relative to control (no …

  • 0 views
  • 21 Mar, 2022
  • 4 locations
HYDROxychloroquine in Syndrome Primary AntiPhospholipid (HYDROSAPL)

, a history of thrombosis, a circulating anticoagulant (ACC) and a triple positivity of antiphospholipids are considered to be factors associated with a poor obstetrical prognosis. Hydroxychloroquine

  • 0 views
  • 12 Mar, 2022
  • 1 location
Hydroxychloroquine in ANCA Vasculitis Evaluation

The purpose of this study is to find out whether hydroxychloroquine, in addition to background treatments, reduces disease activity in patients with Anti-Neutrophilic Cytoplasmic Autoantibodies

  • 0 views
  • 26 Jan, 2021
  • 3 locations
A Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced Melanoma

This study will evaluate the safety, tolerability and efficacy (objective response rate) of using hydroxychloroquine (HCQ) in combination with nivolumab and ipilimumab or with nivolumab alone in

serum pregnancy test
nivolumab
metastatic melanoma
immunologic adjuvant
immunomodulators
  • 0 views
  • 27 Sep, 2021
  • 1 location
Hydroxychloroquine for Prevention of Recurrent Miscarriage.

Antiphospholipid Syndrome. Hydroxychloroquine (HQ) is a molecule whose properties (anti-thrombotic, vascular-protective, immunomodulatory, improved glucose tolerance, lipid-lowering, anti-infectious) could

antiphospholipid syndrome
hydroxychloroquine
heparin
aspirin
miscarriage
  • 412 views
  • 26 Nov, 2021
  • 26 locations
Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer (THREAD)

This phase I trial studies the sides effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer that has spread to nearby tissue

hydroxychloroquine
tumor cells
liver metastasis
measurable disease
cancer
  • 28 views
  • 09 Feb, 2022
  • 1 location
Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer

The PI is studying if sorafenib/hydroxychloroquine (HCQ) will have improved efficacy when compared to sorafenib alone and in patients progressing of sorafenib the addition of HCQ would lead to

advanced hepatocellular cancer
measurable disease
hepatitis
hepatitis b surface antigen
sorafenib
  • 1 views
  • 27 Feb, 2022
  • 1 location
Neoadjuvant mFOLFIRINOX With Perioperative Oral Hydroxychloroquine in Resectable Pancreatic Adenocarcinoma

This will be a phase I/II trial examining the safety and tolerability of pre-operative mFOLFIRINOX in combination with peri-operative oral hydroxychloroquine (FHQ) in the treatment of subjects

  • 0 views
  • 13 Aug, 2021
  • 1 location
Hydroxychloroquine to Increase Tumor Suppressor PAR-4 Levels in Oligometastatic Prostate Cancer

Treatment of recurrent oligometastatic prostate cancer may be enhanced by the addition of Hydroxychloroquine to the current treatment regimens. Potential benefits of Hydroxychloroquine include

androgens
antiandrogen therapy
androgen suppression
  • 0 views
  • 27 Feb, 2022
  • 1 location
Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas (UTAH)

Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.

liver metastasis
measurable disease
cancer
neutrophil count
absolute neutrophil count
  • 0 views
  • 13 Mar, 2022
  • 1 location