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Found 162 clinical trials
FAvipiravir and HydroxyChloroquine Combination Therapy

This study is a randomized, open-label, parallel groups multi-centered trial were participants are assigned to either an intervention arm ( a combination of Favipiravir and Hydroxychloroquin) or standard of care.

oximetry
SARS
hydroxychloroquine
favipiravir
  • 0 views
  • 25 Jan, 2021
  • 10 locations
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of

  • 190 views
  • 01 Aug, 2021
  • 46 locations
Hydroxychloroquine in Prevention of Preeclampsia

, there is no effective or optimal therapeutic approach for these conditions. Hydroxychloroquine has endothelial protective action via ant diabetic, lipid lowering, antioxidant effects or direct

  • 0 views
  • 29 Jul, 2021
  • 1 location
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss

treatment to improve the chance of a live birth. Exciting indications for using Hydroxychloroquine (HCQ) include: Malaria profylaxis and treatment, systemic and discoid lupus erythematosus (SLE) and

discoid lupus erythematosus
malaria
  • 6 views
  • 24 Jan, 2021
  • 1 location
Hydroxychloroquine and Gefitinib to Treat Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common cause of cancer mortality in men and women in Singapore.Chemotherapy and biologically targeted agents can extend survival only modestly for these patients; therefore, discovery of novel ways to prolong the disease course is a top research priority. The epidermal growth factor …

metastasis
pleural effusion
gefitinib
tyrosine
epidermal growth factor
  • 39 views
  • 07 Nov, 2020
  • 1 location
Hydroxychloroquine and Cognitive Function After Surgery

The purpose of this study is to determine whether hydroxychloroquine decreases the relative leakage of the brain barrier after surgery.

  • 42 views
  • 11 Apr, 2021
  • 1 location
Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)

This research study is being done to learn what effect 12 months of treatment with oral hydroxychloroquine (HCQ) will have on the retina in people with retinitis pigmentosa (RP). The hypothesis

antacids
retinal degeneration
genetic testing
retinopathy
genetic analysis
  • 45 views
  • 08 Mar, 2021
  • 1 location
CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine EVErolimus or the Combination for Prevention of Recurrent Breast Cancer

To evaluate the feasibility of administering HCQ, EVE or the combination in patients who have completed primary therapy for breast cancer and harbor bone marrow disseminated tumor cells.

cancer
primary tumor
invasive breast cancer
triple-negative breast cancer
tumor cells
  • 13 views
  • 29 Jul, 2021
  • 1 location
Hydroxychloroquin (HCQ) in chILD of Genetic Defect

The purpose of this proposed research is to investigate the efficacy and safety of hydroxychloroquine sulfate (HCQ, Quensyl) for pediatric ILD(chILD) caused by pulmonary surfactant-associated

  • 0 views
  • 17 Mar, 2021
  • 1 location
MEK and Autophagy Inhibition in Metastatic/Locally Advanced Unresectable Neuroblastoma RAS (NRAS) Melanoma

dosing of 2 milligrams (mg) once a day. Hydroxychloroquine (PLAQUENILR) is an orally available autophagy inhibitor that has been used for many years to treat autoimmune diseases like lupus, sarcoidosis

  • 0 views
  • 25 Jan, 2021
  • 5 locations