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Found 53 clinical trials
Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

dosing regimens of hydrocortisone acetate 90 mg suppository administered with the Sephure applicator for the treatment of ulcerative colitis of the rectum.

  • 2 views
  • 25 Jun, 2021
  • 86 locations
HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome

The primary objective is to demonstrate the superiority of arginine-vasopressin (AVP) and hydrocortisone compared with norepinephrine regarding day-30 survival and neurological recovery in post

  • 0 views
  • 23 Jun, 2021
  • 1 location
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment

This is a controlled, open study designed to compare the effects of dual-release hydrocortisone preparations versus conventional glucocorticoid therapy on clinical, anthropometric parameters

metabolic syndrome
prednisone
deficiency
cortisone acetate
21-ohd
  • 56 views
  • 24 Jan, 2021
  • 1 location
Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock.

The purpose of this randomized controlled trial is to evaluate the hemodynamic effect of low dose corticosteroid therapy (hydrocortisone and fludrocortisone) in the treatment of adult

ejection fraction
oliguria
hypoperfusion
pulmonary artery occlusion
pulmonary congestion
  • 2 views
  • 06 Aug, 2021
  • 37 locations
Prevention of Posttraumatic Stress Disorder (PTSD) With Early Hydrocortisone Treatment: Pilot

decrease symptoms of PTSD. Participants in this study will be randomly assigned to one of two treatment groups. Participants will receive either hydrocortisone (20mg, twice per day) or a

  • 94 views
  • 07 Nov, 2020
  • 1 location
Imaging CRF X NOP Interactions in CUD

This study uses [11C]NOP-1A positron emission tomography (PET) and a hydrocortisone challenge to image the interaction between nociceptive opioid peptide (NOP) receptors and cortisol

  • 0 views
  • 12 Sep, 2021
  • 1 location
[C-11]NPA PET-amphetamine in Cocaine Use Disorders

This study uses [11C]NPA positron emission tomography (PET) and a d-amphetamine challenge to image amphetamine induced dopamine release in the striatum in subjects with cocaine use disorders (CUD). Amphetamine-induced dopamine release data from this study will be correlated with [11C]NOP-1A VT measured at baseline in the midbrain. [11C]NOP-1A PET data …

  • 0 views
  • 12 Sep, 2021
  • 1 location
The WWRD Study: AVM0703 for Treatment of Leukemia or Lymphoma

This is an open-label, Phase 1/2 study designed to characterize the safety, tolerability, Pharmacokinetics(PK), and preliminary antitumor activity of AVM0703 administered as a single intravenous (IV) infusion to patients with lymphoid malignancies.

  • 0 views
  • 23 Sep, 2021
  • 5 locations
Treatment of Acute Lymphoblastic Leukemia Ph '(BCR / ABL) Positive Patients Aged > 55 Years

This study proposes to provide adequate treatment and is based on current scientific evidence for elderly patients with ALL Bcr / Abl positive. To determine whether low-dose chemotherapy associated with imatinib or dasatinib has acceptable tolerability in elderly patients. To determine whether this association can increase the rate and quality …

  • 1 views
  • 28 Jan, 2021
  • 1 location
Single Agent Arsenic Trioxide in the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia

There is very limited data on the use of arsenic trioxide in newly diagnosed patients with acute promyelocytic leukemia. The use of arsenic trioxide was limited to relapsed patients mainly because of the superior efficacy of ATRA as primary therapy for newly diagnosed APML. Though the early study by Niu …

arsenic
hepatic toxicity
remission
tretinoin
  • 76 views
  • 07 Nov, 2020
  • 8 locations