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Found 56 clinical trials
Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage

Vasospasm is a common complication after rupture of intracranial aneurysms causing devastating neurologic deficits and death. Vasospasm has been directly associated with the amount of subarachnoid blood inside the basal cisterns. Prior literature has attempted to refine treatment of ruptured intracranial aneurysms but does not have clear guidelines on the …

intracranial aneurysm
  • 25 Feb, 2022
  • 1 location
Deferiprone for Ruptured Brain Aneurysm

Ruptured cerebral aneurysms lead to subarachnoid hemorrhage (SAH),that has a high morbidity and mortality rate, the severity of which is predicted by the "Hunt-Hess grade" (HHG). SAH leads to iron (Fe) and hemoglobin (Hb) accumulation in the brain, which is toxic for neurons. Ferritin (iron reported in the brian) and …

cognitive disorder
alzheimer's disease
cognitive assessment
  • 12 Apr, 2022
  • 1 location
DCS Study in Extremely Premature Newborns

We are attempting to improve the cerebral monitoring of extremely low gestational age (ELGA) infants, such that in the future, real-time monitoring will be possible, to aid clinicians in their management of these infants. We wish to establish a new NIRS device, diffuse correlation spectroscopy (DCS), as a safe, noninvasive …

cerebral blood flow
intraventricular hemorrhage
cerebral perfusion
premature birth
  • 05 Mar, 2022
External Ventricular Drain Placement Stealth Study

External ventricular drain (EVD) placement is performed very often in neurosurgical practices. EVD's are most commonly placed at the bedside using external anatomical landmarks to guide the catheter into the frontal horn of the ipsilateral lateral ventricle. EVDs are often placed due to acute neurological compromise and require timely insertion. …

  • 19 Apr, 2022
  • 1 location
Endoscopic Third Ventriculostomy for Adults: A Prognostic Model for Success (NordicETV)

Endoscopic Third Ventriculostomy for Adults with Hydrocephalus: Creating a Prognostic Model for Success - A Retrospective Multicenter Study Background: Endoscopic third ventriculostomy

  • 17 May, 2022
  • 12 locations
HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)

The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric

  • 23 Jan, 2022
  • 13 locations
Improving Infant Hydrocephalus Outcomes in Uganda

Neonatal postinfectious hydrocephalus (PIH) is a major public health problem in East Africa.The standard treatment has long been placement of a ventriculoperitoneal shunt (VPS) but these devices

  • 12 May, 2021
  • 3 locations
CPT-3 in Normal Pressure Hydrocephalus

The study will collect prospective cohort data of individuals that are undergoing routine clinical care for suspected idiopathic Normal Pressure Hydrocephalus (NPH). The administration of the

  • 26 Feb, 2022
  • 1 location
Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

The symptoms of hydrocephalus containing consciousness condition with muscle tone in some patients will be relieved, after the cerebrospinal fluid release test is carried out

post-traumatic hydrocephalus
  • 24 Jan, 2021
  • 1 location
Sonographic Monitoring of Weaning of Cerebrospinal Fluid Drainages

As elaborated above only one study reported ultrasonographic changes of the width of the lateral ventricle during clamping of EVD/LD and indicated that ultrasound monitoring might be suitable. No firm data exists about the change of the width of the third ventricle, the diameter of the optic nerve or brain …

optic nerve
brain perfusion
  • 07 Oct, 2021
  • 1 location