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Found 56 clinical trials
Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis

The primary objective is to determine whether Leukotriene A4 hydrolase (LTA4H) genotype, defined at randomisation, determines dexamethasone's clinical effectiveness when added to the first 6-8 weeks of anti-tuberculosis treatment of TBM. The investigators will conduct a LTA4H genotype stratified, parallel group, randomised, double blind, placebo-controlled multi-centre Phase III non-inferiority trial …

tuberculosis treatment
rifampin
meningitis
tb chemotherapy
corticosteroids
  • 53 views
  • 28 Apr, 2022
  • 1 location
Normal Pressure Hydrocephalus and Sleep Apnea

Normal-pressure hydrocephalus is associated with increases in the intracranial pressure during the night sleep. Sleep apnea also increases the intracranial pressure during the apneic spells

  • 7 views
  • 08 Oct, 2021
  • 1 location
Volumetrics and Proteomics in Shunted Normal Pressure Hydrocephalus

Idiopathic normal pressure hydrocephalus (=iNPH) is a condition with disturbed circulation of cerebrospinal fluid (=CSF) causing symptoms such as balance and gait disorders, urinary incontinence

  • 0 views
  • 31 Mar, 2021
  • 1 location
Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

The eShunt System includes proprietary delivery componentry and the eShunt Implant, a permanent implant deployed in a minimally invasive, neurointerventional procedure. The eShunt Implant is designed to mimic the function of the arachnoid granulations by draining excess cerebrospinal fluid (CSF) from the intracranial subarachnoid space (SAS) into the venous system.

  • 0 views
  • 09 Apr, 2022
  • 1 location
US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

The eShunt® System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent

  • 0 views
  • 16 May, 2022
  • 1 location
Idiopathic Normal Pressure Hydrocephalus: Focus on Imaging and Clinical Symptoms. (LiNPH)

LiNPH is a prospective single center clinical and radiological study.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

Participants with known or suspected hydrocephalus will receive brain scans using the Hyperfine, low field strength, portable, magnetic resonance imaging (MRI) system in addition to their

  • 0 views
  • 22 Mar, 2022
  • 1 location
Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement

This study is to prospectively compare Ultrasound guided (US-G) Ventriculoperitoneal Shunt (VPS) placement to stereotactic navigation in a randomized controlled fashion with the surgical intervention time as primary outcome. All patients entering the University Hospital of Basel for elective or emergent VPS surgery will be randomized in 1:1 fashion to …

ventriculoperitoneal shunt
probe
  • 0 views
  • 14 Nov, 2021
  • 1 location
Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage (DRAIN)

To assess the benefits and harms of two commonly used regimens for external ventricular drainage cessation in in patients with hydrocephalus following aneurysmal subarachnoid haemorrhage a

drainage
  • 3 views
  • 10 May, 2022
  • 1 location
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.

normal pressure hydrocephalus
alzheimer's disease
Accepts healthy volunteers
  • 2 views
  • 19 Feb, 2022
  • 1 location