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Found 9 clinical trials
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule

The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule 1.0cm will be

hydatidiform mole
  • 04 Feb, 2022
  • 1 location
Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia (ReCure)

To evaluate the efficacy and safety of second uterine curettage in patients with low-risk non-metastatic GTN.

  • 04 Jun, 2022
  • 6 locations
Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment

Gestational trophoblastic neoplasias (GTN) are characterized by the persistence of elevated hCG titers after complete uterine evacuation of a partial hydatidiform mole (PHM) or a complete

  • 24 Jan, 2021
  • 6 locations
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

The investigators conducted a randomized trial to study how well multi-day methotrexate protocol works compared to biweekly single-dose actinomycin D protocol in treating patients with low-risk gestational trophoblastic neoplasia. It is not yet known whether multi-day methotrexate protocol is as effective as biweekly single-dose actinomycin D protocol in treating patients …

serum bilirubin
  • 24 Nov, 2021
  • 1 location
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

Study of hysteroscopic repeat curettage as the first-line treatment in low-risk postmolar gestational trophoblastic neoplasia compared with the MTX single drug chemotherapy

total bilirubin
serum bilirubin
trophoblastic disease
  • 04 Oct, 2022
  • 1 location
The French National Reference Centre of GTD

The French Gestational Trophoblastic Disease (GTD) centre has been set up and active by registering, monitoring and treating women with GTD since november 1999. The aim is to improve the management of trophoblastic disease in France. About 850 new cases are registered each year and 140 women treated, mostly with …

hydatidiform mole
human chorionic gonadotrophin
chest radiography
trophoblastic disease
  • 21 Jan, 2021
  • 1 location
BioMEL- Diagnostic and Prognostic Factors in Melanoma. (BioMEL)

The investigators' hypothesis is that cutaneous melanoma, melanoma in situ, dysplastic nevi and benign nevi all differ in not only clinical characteristics but also molecular and genotypic characteristics. Patients with suspected primary cutaneous melanoma or a differential diagnosis, or secondary melanoma can be asked to participate in the first part …

metastatic melanoma
melanoma skin
malignant melanoma of skin
skin lesion
  • 07 Oct, 2022
  • 4 locations
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles

The researchers' laboratory is studying a rare class of highly recurrent hydatidiform moles. These are usually complete hydatidiform moles (CHM), but sometimes they are partial hydatidiform moles PHM). With sporadic moles, the difference between CHMs and PHMs is that with CHMS, there is not typically an embryo or fetus at …

Accepts healthy volunteers
  • 18 May, 2022
  • 1 location
The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles

This is a prospective observational study assessing which ultrasound findings are best at excluding a molar pregnancy in first trimester miscarriage.

  • 07 Oct, 2022
  • 2 locations