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Found 85 clinical trials
Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome (TimeMAP)

Polycystic ovarian syndrome (PCOS) is associated with metabolic symptoms such as hyperinsulinemia. Time-restricted eating may reduce serum insulin and improve insulin resistance in patients with PCOS. Currently, there are few studies investigating time-restricted eating in patients with PCOS. The investigators plan to test the feasibility of time-restricted eating in the …

oligomenorrhea
hyperandrogenism
Accepts healthy volunteers
insulin
fasting
  • 0 views
  • 18 Jun, 2022
  • 1 location
2-A-Day Study: Twice a Day Meals Study.

Caloric restriction increases lifespan and/or healthspan across multiple species. However implementation of long-term CR in humans is problematic and unacceptable to many individuals. As a result, intermittent fasting models have been developed to improve adherence. Such models have been shown to improve blood pressure, insulin sensitivity, decrease hepatic fat content …

oral glucose tolerance test
insulin
diabetes
insulin sensitivity
plasma glucose
  • 351 views
  • 24 Mar, 2022
  • 1 location
Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis

Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to …

acute pancreatitis
Accepts healthy volunteers
abdominal pain
lipase
amylase
  • 0 views
  • 27 Dec, 2021
  • 1 location
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function

The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear. Thus, the present study will assess sleep and stigma as possible moderators. As sleep is related to both weight and …

  • 17 views
  • 02 Oct, 2021
  • 1 location
Unintentional Weight Loss After Oesophagectomy (UWL)

The incidence of cancer of the oesophagus is increasing. While surgical removal of the tumour (oesophagectomy) may offer the best chance of cure, such major operations are associated with long-term complications such as poor appetite, unintentional weight loss and nutritional impairments. In the long-term, unintentional weight loss of 10-30% increases …

Accepts healthy volunteers
adenocarcinoma
  • 0 views
  • 05 May, 2022
  • 1 location
Time Restricted Eating (TRE) Among Native Hawaiian/Pacific Islander Women at Risk for Endometrial Cancer (TIMESPAN)

The long-term goal of this study is to determine the efficacy of time restricted eating (TRE) for improving metabolic health and preventing endometrial cancer. The primary objective of the protocol is to conduct a 14-week two-arm randomized crossover trial of a dietary intervention to evaluate the feasibility, fidelity and preliminary …

Accepts healthy volunteers
cancer
insulin
diabetes
hyperplasia
  • 0 views
  • 24 May, 2022
  • 1 location
Impacts of Lentils on Metabolism and Inflammation

The overall goal of this investigation is to determine gut microbiome dependent and independent impacts of pulse consumption on metabolic resilience and metabolic risk profiles for type 2 diabetes (T2D) and cardiovascular disease (CVD) risk. Specifically, pulse crop consumption has unrealized potential to fundamentally alter how the body responds to …

cardiovascular disease
type 2 diabetes mellitus
diabetes
fasting
fats
  • 436 views
  • 19 Jun, 2022
  • 1 location
Program for the Comprehensive Neurocognitive Treatment of Excess Weight

The present study aims to determine the effectiveness of a comprehensive neurocognitive program for the treatment of excess weight. The program will include sessions to improve multiple cognitive processes implicated in weight gain and obesity. These cognitive processes include approach-avoidance bias, inhibition control, implementation intentions and episodic future thinking. Participants …

Accepts healthy volunteers
overweight and obesity
  • 6 views
  • 29 Dec, 2021
  • 1 location
Adapted Motivational Interviewing and Cognitive Behavioural Therapy for Food Addiction (AMI+CBTforFA)

Food addiction is the concept that individuals can be "addicted" to foods, particularly highly processed foods. This concept has attracted growing research interest given rising obesity rates and the engineering of food products. Although food addiction is not a recognized mental disorder, individuals do identify as being addicted to foods …

behavior therapy
addictive behaviors
psychotic
  • 4 views
  • 13 May, 2022
  • 1 location
Effects of Intermittent Fasting on Insulin Resistance, Cardiac Metabolism, and Cerebral Perfusion

The overall purpose of the study is to investigate whether three weeks of intermittent fasting (alternate-day fasting, (ADF)) result in a more pronounced "metabolic shift" towards the use of ketone bodies than three weeks of Western diet. The investigators will use state-of-the-art PET/CT tracer techniques and well-established steady state kinetics …

Accepts healthy volunteers
  • 0 views
  • 27 May, 2022
  • 1 location