Found 22 clinical trials
LCCC 2044: Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
circulating HPV DNA in blood plasma. The study will also investigate whether HPV integration is associated with TRAF3 and CYLD mutations, and whether recurrence prediction improves when looking at HPV
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- 19 Oct, 2022
- 1 location
Newer Therapeutic Targets in Head and Neck Cancers
Based on the recently identified mutations in HNSCCs, the major pathologic pathways implicated in the tumorigenesis of HNSCC include dysregulation of four processes: cellular survival and proliferation (e.g., TP53, EGFR, MET, and PIK3CA); cell-cycle control (e.g., CDKN2A and CCND1); cellular differentiation (e.g., NOTCH1); and Adhesion and invasion signaling (e.g., FAT1).7 …
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- 04 Jun, 2022
- 1 location