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Found 136 clinical trials
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A Study of BPI-1178 in Patients With Advanced Solid Tumor and HR+/HER2- Breast Cancer

pharmacokinetics of BPI-1178 in subjects with advanced solid tumor, as well as the subjects with advanced hormone receptor-positive(HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer.

aptt
letrozole
thromboplastin
HER2
erbb2
  • 0 views
  • 08 Aug, 2021
  • 1 location
None
Anti-HER2 Bispecific Antibody ZW25 Activity in Combination With Chemotherapy With/Without Tislelizumab

The purpose of the study is to assess the safety, tolerability and preliminary antitumor activity of ZW25 in combination with docetaxel in participants with human epidermal growth factor

cancer treatment
HER2
erbb2
growth factor
human epidermal growth factor
  • 0 views
  • 21 Nov, 2021
  • 22 locations
None
Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer

epidermal growth factor receptor-2 (HER-2) positive primary breast cancer.

core needle biopsy
epidermal growth factor
HER2
primary tumor
growth factor
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
A Study of ZW25 (Zanidatamab) With Palbociclib Plus Fulvestrant in Patients With HER2+/HR+ Advanced Breast Cancer

. Eligible patients include those with locally advanced (unresectable) and/or metastatic human epidermal growth factor receptor 2 (HER2)-positive, hormone receptor (HR)-positive breast cancer.

  • 0 views
  • 01 Jul, 2021
  • 15 locations
None
A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases

advanced or metastatic human epidermal growth factor receptor 2 (HER2) positive breast cancer and HER2-positive advanced breast cancer with liver metastasis.

invasive breast cancer
HER2
stage iv breast cancer
erbb2
growth factor
  • 128 views
  • 17 Jul, 2021
  • 69 locations
None
MEtronomic TrEatment Option in Advanced bReast cAncer

This is a multi-center, randomized phase II trial that will randomise women with ER-positive, HER2-negative (Human Epidermal Growth factor Receptor 2-negative) metastatic or locally relapsed

epidermal growth factor
HER2
erbb2
stage iv breast cancer
growth factor
  • 58 views
  • 24 Jan, 2021
  • 24 locations
None
A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer

combination with abemaciclib (VERZENIO) in participants with advanced estrogen-receptor positive, human epidermal growth factor receptor-2 negative (ER+/HER2-) breast cancer.

epidermal growth factor
HER2
measurable disease
estrogen receptor
erbb2
  • 2 views
  • 27 Nov, 2021
  • 6 locations
None
A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Solid Tumors (MK-2140-002)

-negative breast cancer (TNBC), non-squamous non-small-cell lung cancer (NSCLC), estrogen receptor-positive breast cancer, progesterone receptor-positive breast cancer and human epidermal growth factor 2

epidermal growth factor
estrogen receptor
measurable disease
growth factor
mammogram
  • 0 views
  • 24 Nov, 2021
  • 5 locations
None
Combined Immunotherapies in Metastatic ER+ Breast Cancer

Women with Hormone Receptor (HR)+ Human Epidermal growth factor Receptor (HER)2- metastatic breast cancer are eligible to a randomized trial. Patients receiving standard first line therapy for

letrozole
epidermal growth factor
HER2
measurable disease
erbb2
  • 0 views
  • 11 Jul, 2021
  • 5 locations
None
Elacestrant in Preoperative Setting a Window of Opportunity Study

Estrogen Receptor-positive (ER+) and Human Epidermal Growth Factor Receptor 2-negative (HER2-negative) early breast cancer (BC) amenable to surgery.

epidermal growth factor
HER2
estrogen receptor
erbb2
growth factor
  • 0 views
  • 20 Jun, 2021
  • 4 locations