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Found 136 clinical trials
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Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy

The introduction of trastuzumab for the treatment of patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer has had a major impact upon cancer outcomes. However

trastuzumab
her2/neu-positive breast cancer
HER2
erbb2
  • 0 views
  • 30 Aug, 2021
  • 1 location
None
Phase II Study of Pembrolizumab and Nab-paclitaxel in HER-2 Negative Metastatic Breast Cancer

death 1 (PD-1), pembrolizumab, in patients with human epidermal growth factor receptor (HER-2) negative metastatic breast cancer (n=50). There will be two cohorts of patients consisting of a triple

epidermal growth factor
HER2
endocrine therapy
growth factor
hormone therapy
  • 2 views
  • 24 Sep, 2021
  • 1 location
None
Personalised Disease Monitoring in Metastatic Breast Cancer

Patients with metastatic breast cancer may respond well to treatment and metastases can remain stable for several years. Despite personalised medicine being increasingly used for diagnosis and treatment, follow-up still include radiological response evaluation every 3-4 months, which renders a significant number of 'unnecessary' exams for patients with long-term stable …

  • 0 views
  • 28 Nov, 2021
  • 7 locations
None
Study on Bisphosphonates Targeting Triple-negative Breast Cancer

Triple-negative breast cancer has a poor prognosis and lacks effective adjuvant treatment. A number of preclinical and clinical trials have shown that bisphosphonates have direct or indirect anti-tumor activity, and early use of bisphosphonate adjuvant therapy can prevent cancer recurrence and metastasis including bone metastasis and greatly improve the prognosis …

HER2
estrogen
progesterone receptor
mammogram
metastasis
  • 0 views
  • 30 Jul, 2021
  • 3 locations
None
CTC Changes and Efficacy of Neoadjuvant Chemotherapy for Triple-negative Breast Cancer

Chemotherapy before operation for malignant tumors can reduce the size of tumors to a certain extent, even eliminate micrometastases. Chemotherapy can also detect the sensitivity of chemotherapeutic drugs and create opportunities for breast-conserving or surgical treatment for patients. This may lead to high survival opportunities for triple-negative breast cancer patients …

taxane
mammogram
cancer chemotherapy
anthracyclines
hormone therapy
  • 1 views
  • 28 Jan, 2021
  • 2 locations
None
Circulating Tumor Cell Detection in Patients With Luminal A Breast Cancer

The incidence of breast cancer in Chinese women has increased year by year, and luminal A breast cancer commonly occurs in early-stage and postmenopausal women. This type of breast cancer is not sensitive to chemotherapy, although it has a low mortality rate and distant metastasis rate. Studies have shown that …

estrogen
progesterone receptor
metastasis
growth factor
hormone therapy
  • 3 views
  • 28 Jan, 2021
  • 2 locations