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Found 140 clinical trials
EndoPredict® Extended Endocrine Trial (EXET)

The purpose of this study is to evaluate the impact of using EndoPredict clinically to inform treatment decisions for extended endocrine therapy, and the subsequent impact on patient outcomes.

breast carcinoma
erbb2
invasive breast cancer
hormone therapy
endocrine therapy
  • 21 views
  • 12 Feb, 2022
  • 45 locations
Real-world Treatment Patterns of Endocrine Based Therapy Among Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor-2-negative (HR+/HER2-) Advanced Breast Cancer: An Analysis of Administrative Claims Data in Japan

This is a retrospective observational study focusing on patients diagnosed with advanced breast cancer(ABC) in Japan using de-identified claim data from Medical Data Vision (MDV) database. The primary objective of this study is to describe patient demographics, treatment patterns and treatment duration of palbociclib, and subsequent treatment patterns and treatment …

erbb2
EGFR
hormone therapy
growth factor
epidermal growth factor receptor
  • 0 views
  • 17 Dec, 2021
  • 1 location
Determinants of Acquired Endocrine Resistance in Metastatic Breast Cancer: A Pilot Study (ENDO-RESIST)

therapy with an aromatase inhibitor in combination with an inhibitor of the cyclin-dependent kinases 4 and 6 (CDK 4/6). Up to 20 patients with Estrogen Receptor positive (ER+), Human Epidermal Growth

  • 0 views
  • 18 May, 2022
  • 1 location
Real-life Pan-HER-blockade With Neratinib

So far, there is no data available on treatment of patients with early-stage hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2)-overexpressed/amplified breast cancer

cancer
erbb2
EGFR
breast cancer
breast cancer staging
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy

The introduction of trastuzumab for the treatment of patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer has had a major impact upon cancer outcomes. However

trastuzumab
her2/neu-positive breast cancer
HER2
erbb2
  • 0 views
  • 30 Aug, 2021
  • 1 location
CT-based Radiomics of ALN pCR (ypN0) in Breast Cancer Undergoing NAC

This is a prospective, single-center, non-randomized, non-controlled observational study.

  • 0 views
  • 01 May, 2022
  • 1 location
Study on Bisphosphonates Targeting Triple-negative Breast Cancer

Triple-negative breast cancer has a poor prognosis and lacks effective adjuvant treatment. A number of preclinical and clinical trials have shown that bisphosphonates have direct or indirect anti-tumor activity, and early use of bisphosphonate adjuvant therapy can prevent cancer recurrence and metastasis including bone metastasis and greatly improve the prognosis …

progesterone receptor
erbb2
estrogen receptor
estrogen
bisphosphonate
  • 2 views
  • 30 Jul, 2021
  • 3 locations
Personalised Disease Monitoring in Metastatic Breast Cancer

Patients with metastatic breast cancer may respond well to treatment and metastases can remain stable for several years. Despite personalised medicine being increasingly used for diagnosis and treatment, follow-up still include radiological response evaluation every 3-4 months, which renders a significant number of 'unnecessary' exams for patients with long-term stable …

  • 0 views
  • 28 Nov, 2021
  • 7 locations
CTC Changes and Efficacy of Neoadjuvant Chemotherapy for Triple-negative Breast Cancer

Chemotherapy before operation for malignant tumors can reduce the size of tumors to a certain extent, even eliminate micrometastases. Chemotherapy can also detect the sensitivity of chemotherapeutic drugs and create opportunities for breast-conserving or surgical treatment for patients. This may lead to high survival opportunities for triple-negative breast cancer patients …

taxane
mastectomy
cancer chemotherapy
cancer
anthracyclines
  • 1 views
  • 25 Mar, 2022
  • 2 locations
Circulating Tumor Cell Detection in Patients With Luminal A Breast Cancer

The incidence of breast cancer in Chinese women has increased year by year, and luminal A breast cancer commonly occurs in early-stage and postmenopausal women. This type of breast cancer is not sensitive to chemotherapy, although it has a low mortality rate and distant metastasis rate. Studies have shown that …

EGFR
progesterone
breast cancer
tumor cells
growth factor
  • 3 views
  • 15 May, 2022
  • 2 locations