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Found 863 clinical trials
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's tissues. In oral cGVHD, the tissues in the mouth are

graft-versus-host disease
graft versus host disease
  • 160 views
  • 22 Dec, 2020
  • 1 location
Featured trial
The Health and Aging Brain Study: Health Disparities

Alzheimer’s disease is the most common cause of memory problems as we age. However, many things can impact our thinking over time. At HSC, we are working to find new and better ways to treat and

alzheimer's disease
Accepts healthy volunteers
  • 19 views
  • 14 Jun, 2022
  • 1 location
Featured trial
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

cell transplant with fewer complications. Objectives: To evaluate a new method of stem cell transplantation that may reduce the possibly of severe side effects

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 190 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

Background: Cord blood is blood that is taken from the umbilical cord and placenta of healthy newborns after childbirth. The cord blood collected from a baby is called a cord blood unit. Cord blood units are stored frozen in public cord blood banks. About 10,000 cord blood transplants have been …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 79 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

the patient s healthy tissues. The average hospital stay after stem cell transplantation is 3 to 4 weeks. Patients return for frequent follow-up visits for the first 2 to 4 months after

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 54 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the

sickle cell disease
stroke
cell transplantation
red blood cell disorder
  • 83 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS)

  • 312 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Background: People with severe aplastic anemia (SAA) do not make enough red and white blood cells, and/or platelets. Their body's immune system stops the bone marrow from making these cells. The treatment cyclosporine leads to better blood counts. But when this treatment is stopped, the disease may return in 1 …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 75 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 75 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications

Background: Cord blood transplants can treat cancers and other diseases in children and adults. The U.S. Food and Drug Administration (FDA) requires cord blood to be collected and stored under certain safety standards. However, most available cord blood units were collected before the FDA set these standards. These units may …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia
aplastic anemia
anemia studies
  • 57 views
  • 22 Dec, 2020
  • 1 location