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Found 12 clinical trials
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A Study to Assess the Safety Tolerability and Immunological Response of ASP2390 in Adult Subjects Allergic to House Dust Mites

The purpose of this study is to evaluate the safety and tolerability of multiple ascending intradermal doses of ASP2390 in adult male and female participants allergic to house dust mites (HDM

  • 2 views
  • 10 Oct, 2021
  • 2 locations
None
A Research Study in Chinese People With Allergy to House Dust Mites Using an Environmental Exposure Chamber

This trial evaluates the efficacy and safety of HDM SLIT-tablet in treatment of HDM AR. The efficacy is evaluated using an environmental exposure chamber (EEC). Subjects will be randomised to receive treatment with HDM SLIT-tablet and placebo 1:1.

asthma
environmental exposure
  • 0 views
  • 27 Feb, 2021
  • 2 locations
None
Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy

The aim of the study is: to evaluate the serum levels of miR-223 and miRNA146a and to assess their correlation with disease severity in allergic rhinitis patients and their role as biomarkers for efficacy of sublingual immunotherapy. also to find if high sensitivity CRP can be an easy non-expensive test …

  • 0 views
  • 28 Sep, 2021
  • 1 location
None
Diagnostic Accuracy of the MADx Multi Array Xplorer (MAX 45k) Automated Laboratory System and the MADx Allergy Explorer Version 2 (ALEX ) - IgE Multiplex Test for the Diagnosis of Pre-defined Groups of Specific High-priority Allergens

allergies (e.g. grass pollen, house dust mite or cat allergy) will be included as well as patients suffering from Hymenoptera venom allergy, which is the major cause of anaphylaxis.

  • 11 views
  • 09 Sep, 2021
  • 2 locations
None
Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients

The present study investigates the reaction of the skin upon exposure to house dust mite (HDM) in patients with atopic dermatitis who have antibodies against HDM in the blood. A further aim is

hysterectomy
tubal ligation
allergen
allergic rhinitis
  • 0 views
  • 21 Oct, 2021
  • 2 locations
None
Mediators in Nasal Hyperreactivity in Allergic Rhinitis and Chronic Rhinosinusitis

Rhinitis, or inflammation of the nasal mucosa, can present with nasal obstruction, nasal discharge, itch or sneezing. If the sinusal mucosa is involved as well, it is called rhinosinusitis and facial pain or loss of smell is possible. Several causes are known, such as an underlying allergy ("allergic rhinitis", AR). …

  • 0 views
  • 18 Sep, 2021
  • 1 location
None
Efficacy and Safety Evaluation for the Treatment of Asthma and Allergic Rhinitis/Rhinoconjunctivitis

in patients with mild to moderate asthma and allergic rhinitis/rhinoconjunctivitis (intermittent or persistent) due to hypersensitivity to house dust mites (Dermatophagoides pteronyssinus and / or D

tubal ligation
dermatophagoides farinae
rhinitis
dermatophagoides pteronyssinus
asthma
  • 1 views
  • 01 Oct, 2021
  • 14 locations
None
Assessing the Expression and the Activity of Rac1 Protein in the Airway Smooth Muscle of Asthmatic Patient

contraction of airway smooth muscle cells. They show that Rac1 is expressed in the airway smooth muscle cells in mice and its activity is increased in the bronchi of asthma induced mice sensitized to House

pulmonary function test
wheezing
corticosteroids
dust mite
bronchodilator
  • 0 views
  • 08 Apr, 2021
  • 1 location
None
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection. The secondary objectives are to determine duration and severity of each acute episode with acute expiratory breathing difficulty, the number of episodes …

wheezing
corticosteroid therapy
corticosteroids
steroid therapy
  • 34 views
  • 28 Jun, 2021
  • 10 locations
None
Impact of Exposure to Environmental Pollutants on Birth Outcomes in an Israeli Cohort

, house dust, and in the food supply, resulting in exposure to humans. Characterizing the extent of exposure and the effects of exposure in vulnerable populations, such as pregnant women and children, is

  • 1 views
  • 21 Jan, 2021
  • 2 locations