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Found 76 clinical trials
Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia

CDH is associated with lung hypoplasia, pulmonary hypertension, and left ventricular hypoplasia. Use of new STE techniques (heart ultrasound) showed that CDH newborns have decreased LV size and function, potentially explaining the non-response to iNO, and that these cardiac findings were associated with poor outcomes. Our hypothesis: CDH newborns persist …

hypertension
pulmonary hypoplasia
diaphragmatic hernia
Accepts healthy volunteers
  • 0 views
  • 27 Feb, 2022
  • 1 location
Study of Selected X-Linked Disorders: Aicardi Syndrome

Based on our current understanding of Aicardi syndrome, the condition is hypothesized to occur due to a genetic change on the X-chromosome. The research team is investigating Aicardi syndrome to identify the specific gene location associated with the disorder. Th investigators are collecting blood and skin biopsy samples from patients …

  • 5 views
  • 03 May, 2022
  • 1 location
Pregnancies Complicated by Fetal Anomalies (FAR)

The focus of this research is to create a repository of ultrasonographic images and their corresponding medical data from pregnant women (the mothers of the fetuses that are imaged), focusing on fetal anomalies. These women will visit the obstetrical clinics at Regional One Health and the Le Bonheur Fetal Center.

prenatal
  • 20 views
  • 04 Jun, 2022
  • 5 locations
Maternal-fetal Immune Responses to Fetal Surgery

Performing surgery in utero on fetuses with certain birth defects has led to significant improvements in outcomes after birth; however, many of these infants are born preterm which can decrease the effectiveness of these procedures. The investigators aim to understand the effects of surgery on the maternal and fetal immune …

  • 0 views
  • 27 Apr, 2022
  • 3 locations
Flourish™ Pediatric Esophageal Atresia

This study is continued evaluation of the safety and probable benefit of the Flourish Pediatric Esophageal Atresia device through the Humanitarian Device Exemption (HDE) pathway.

  • 20 views
  • 15 Jun, 2022
  • 8 locations
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Each year world-wide, 2.5 million fetuses die unexpectedly in the last half of pregnancy, 25,000 in the United States, making fetal demise ten-times more common than Sudden Infant Death Syndrome. This study will apply a novel type of non-invasive monitoring, called fetal magnetocardiography (fMCG) used thus far to successfully evaluate …

holter monitor
diagnostic procedure
prenatal
electrocardiogram
  • 0 views
  • 15 Dec, 2021
  • 2 locations