Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 68 clinical trials
Whole Genome Medical Sequencing for Genome Discovery

Background A number of rare inherited diseases affect only a few patients, and the genetic causes of these conditions remain unknown. Researchers are studying the use of a new technology called whole genome sequencing to learn which gene or genes cause these conditions. Understanding the genes that cause these diseases …

genetic test
MRI
genetic testing
skin biopsy
x-rays
  • 101 views
  • 28 Jul, 2022
  • 1 location
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies

The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or congenital anomalies, which provide vital support and research foundation for accurate diagnosis, precision treatment and meticulous management.

prenatal
intrauterine growth retardation
  • 5 views
  • 09 Feb, 2022
  • 1 location
Environmental Factors and Embryonic Development Project (EFED)

The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.

Accepts healthy volunteers
  • 0 views
  • 20 Feb, 2022
Diaphragmatic Hernia Research & Exploration Advancing Molecular Science

The goal of this study is to identify genes that convey susceptibility to congenital diaphragmatic hernia in humans. The identification of such genes, and examination of their structure and function, will enable a delineation of molecular pathogenesis and, ultimately, prevention or treatment of congenital diaphragmatic hernia. There are many different …

cancer
hypertension
diaphragmatic hernia
diabetes
linkage analysis
  • 120 views
  • 28 Oct, 2021
  • 15 locations
Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology (CAUSE)

The CAUSE study is a multicenter study, with domestic (n=4) and international (n=6) study sites. Children and young adults (ages 0-18) who have microtia and/or craniofacial microsomia and their parents are invited to participate. Children and parents are asked to provide a DNA sample (blood or saliva) and are asked …

  • 2 views
  • 05 Mar, 2022
  • 9 locations
Mayo AVC Registry and Biobank

Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease process can be subtle, but …

dilated cardiomyopathy
cardiomyopathy
genetic condition
cardiac death
fibrillation
  • 228 views
  • 11 May, 2022
  • 2 locations
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

There is a variety of tumors affecting the pituitary gland in childhood; some of these tumors (eg craniopharyngioma) are included among the most common central nervous system tumors in childhood. The gene(s) involved in the pathogenesis of these tumors are largely not known; their possible association with other developmental defects …

cushing's syndrome
central nervous system tumors
craniopharyngioma
linkage analysis
pituitary
  • 181 views
  • 08 Aug, 2022
  • 1 location
Assessment of Adherence Quality of Life Clinical Response and Safety of Daily and Long-Acting Growth Hormone Therapy

children with growth hormone deficiency (GHD). These objectives will be evaluated every 6 months for subjects prior to switch from DGH to LAGH, and 6 months after.

  • 0 views
  • 16 Oct, 2021
  • 1 location
Skeletal Muscle Effects of GH in Boys

The purpose of the study is to measure the functional effects of recombinant GH in skeletal muscle, in addition to growth promotion, in short prepubertal boys with either growth hormone

somatotropin
GH deficiency
Accepts healthy volunteers
somatropin
pituitary hormone
  • 0 views
  • 06 May, 2022
  • 1 location
Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors

There is currently no prognostic or predictive risk marker for this urethral stricture disease. The most conservative standard treatment for urethral stricture (internal urethrotomy) has a very high recurrence rate (greater than 75%) and, on many occasions, reconstructive urologists have to choose within a great variety of further complex interventions. …

  • 8 views
  • 19 Mar, 2021
  • 1 location