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Found 72 clinical trials
Growth Hormone Replacement Therapy for Retried Professional Football Players

professional football players with growth hormone deficiency (GHD).

growth hormone
  • 06 Aug, 2021
  • 1 location
PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism

This study is limited to conduct in China only. The primary objective is to assess the treatment effect of daily TransCon PTH on serum calcium (sCa) levels within the normal range and stopping from therapeutic doses of active vitamin D (calcitriol) or active vitamin D analogue (alfacalcidol) and calcium at …

  • 04 Jun, 2022
  • 1 location
Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X)

the primary efficacy endpoints that will be evaluated in TRIIM-X. Somatropin is approved by the FDA for adult growth hormone deficiency and its use in the study is guided by prior safety data

Accepts healthy volunteers
  • 05 Mar, 2022
  • 1 location
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete spinal cord injury. The investigators hypothesize that LT+TRT treatment …

testosterone level
spinal cord
incomplete spinal cord injury
spinal cord disorder
  • 12 Sep, 2021
  • 2 locations
Paricalcitol Improves Anemia of Inflammation

Anemia of inflammation (AI) is a common comorbidity in hemodialysis patients. Paricalcitol is a selective vitamin D receptor activator with potential benefits on anti-inflammatory cytokines expression. The paricalcitol for the secondary hyperparathyroidism control may improve AI decreasing erythropoietin stimulating agents (ESAs) dosage.

epoetin beta
transferrin saturation
  • 13 Mar, 2021
  • 1 location
A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

This clinical trial will use growth hormone as a novel treatment for Phelan-McDermid syndrome (PMS) and idiopathic autism. A double-blind, placebo-controlled crossover trial design will be used in 30 children with idiopathic autism and 15 children with PMS to evaluate the the effects of growth hormone on visual evoked potentials …

  • 15 Jun, 2022
Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO)

The rationale for fetal therapy in severe congenital diaphragmatic hernia (CDH) is to restore adequate lung growth for neonatal survival.

diaphragmatic hernia
fetal therapy
pulmonary hypoplasia
  • 24 Jan, 2021
  • 1 location
High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia

The purpose of this study is to conduct a prospective study of all congenital diaphragmatic hernia (CDH) neonates managed at the University of Utah newborn intensive care unit (NICU) and Primary Children's Hospital NICU that required mechanical ventilation at birth. As both high frequency jet ventilation (HFJV) and high frequency …

  • 14 Mar, 2021
  • 2 locations
Intact Cord Resuscitation in CDH

Isolated CDH is a rare disease (1/3500) and displays a wide range of severity and outcome. Despite attempts to standardize the management of this disease at birth and during the first months of life, the mortality varies from 20 to 50% according to different hospitals in France and abroad. Several …

  • 02 May, 2021
  • 3 locations
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the …

fetal therapy
nitric oxide therapy
pulmonary hypoplasia
nitric oxide
  • 14 Oct, 2021
  • 1 location