Found 4 clinical trials
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Unknown Phase
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users
HMG-CoA reductase inhibitors (statins) have beneficial effects (prevent stroke, heart attack) but also some bad ones (block some good effects of exercise). Individuals have genetic variations in proteins that metabolize/transport statins. We hypothesize that these variations modulate the relationship between statin use and lack of benefit from exercise. We will …
- 0 views
- 29 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome
This study evaluate the efficacy of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-COA) reductase inhibitors, also known as "statins" in the treatment of growth and skeletal abnormalities in children with Noonan syndrome. Half of patients will receive simvastatin while the other half will receive a placebo.
- 24 views
- 16 Nov, 2020
- 20 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Infections and Infectious Diseases
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Currently Recruiting
Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging
The purpose of this study is to determine whether HMG-CoA reductase inhibitor, atorvastatin attenuates inflammation in atherosclerotic plaques detected by 18F-fluorodeoxyglucose(FDG) PET.
- 4 views
- 07 Nov, 2020
- 1 location
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Unknown Phase
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Neurology
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Currently Recruiting
Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors
In this study, the investigators will examine the association of statin use and dyskinesia in a convenience sample Parkinson's disease patients in the Veterans Administration Health Care System.
- 2 views
- 24 Sep, 2020
- 3 locations