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Found 34 clinical trials
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

This phase I trial studies the side effects and best dose of nivolumab when given with ipilimumab in treating patients with human immunodeficiency virus (HIV) associated classical Hodgkin lymphoma that has returned after a period of improvement or does not respond to treatment, or solid tumors that have spread to …

ipilimumab
nivolumab
lipase
mitomycin
solid tumour
  • 182 views
  • 13 Aug, 2021
  • 35 locations
Treatment of Early Hypertension Among Persons Living With HIV in Haiti

The investigators are conducting an unblinded pilot randomized control trial of 250 persons living with HIV (PLWH), aged 18-65 years, who receive antiretroviral therapy care at Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), are virally suppressed, and have pre-hypertension (systolic blood pressure (SBP) 120-139 or …

  • 0 views
  • 30 Mar, 2021
  • 1 location
HIV Reengagement and Assessment Mobile Program (Project RAMP)

The North Carolina Bridge Counselor system is designed to help link out of care HIV positive patients back into HIV care. It has improved initial linkages and patient re-engagement overall, but for a sizable group of patients, the current system has not been effective, leaving a population of hard-to-reach, lost-to-care …

antiretroviral agents
antiretroviral therapy
  • 0 views
  • 19 Mar, 2021
  • 1 location
University of Utah COVID-19 Hydrochloroquine Trial

A novel coronavirus, SARS-CoV-2, is responsible for a rapidly spreading pandemic that has reached 160 countries, infecting over 500,000 individuals and killing more than 24,000 people. SARS-CoV-2 causes an acute and potentially lethal respiratory illness, known as COVID-19, that is threatening to overwhelm health care systems due to a dramatic …

nucleic acid
hydroxychloroquine
covid-19
antiviral drugs
SARS
  • 109 views
  • 26 Jan, 2021
  • 1 location
Immunogenicity and Safety of a 9-valent Human Papillomavirus Vaccine in HIV-positive Women

In adult HIV-positive patients, data on the safety and immunogenicity of the quadrivalent HPV (qHPV) vaccine have been reported with excellent results (13 14); also, the results of a clinical trial of qHPV vaccine conducted in seropositive patients older than 36 years (WLHIV and MSM) have been published. Even now, …

human papillomavirus
hpv vaccine
HIV Vaccine
  • 15 views
  • 24 Jan, 2021
  • 1 location
PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection

Background HIV affects millions of people. The disease may "hide" in the brain, even in people with well-controlled HIV without cancer. Then it may "wake up" and continue. The drug pembrolizumab uses the body s immune system to fight cells like cancer cells. It is approved to treat some cancers …

immune globulin
hiv-1 infection
wbc count
hysterectomy
antiretroviral therapy
  • 14 views
  • 09 May, 2021
  • 1 location
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies, such as among people living with HIV or those with prior history of transplant. Researchers want to see if 2 non-chemotherapy drugs can help people with KS. …

monoclonal antibodies
doxorubicin
systemic therapy
protease
cancer chemotherapy
  • 12 views
  • 12 Sep, 2021
  • 1 location
PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

ART will have screening blood tests for CD4 count, HIV viral load and genetic testing. After the screening blood tests and before starting HIV medicines., participants will return for more

  • 0 views
  • 16 Aug, 2021
  • 1 location
A Long-term Follow-up of the HIV-NAT Cohort

further insights into the long-term safety and durability of various antiretroviral therapeutic approached, the efficacy of HIV viral load and CD4 cell counts as predictors of disease progression and

antiretroviral agents
antiretroviral
hiv viral load
AIDS
HIV Vaccine
  • 2 views
  • 25 Jan, 2021
  • 1 location
Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir

). Measurements in mothers will include demographics and health status, HIV disease and ART use, intercurrent medical history including concomitant medication use, HIV viral load testing, ART adherence, HIV

dolutegravir
insulin
hiv viral load
antiretroviral therapy
emtricitabine
  • 0 views
  • 13 Aug, 2021
  • 2 locations