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Found 69 clinical trials
Simunye: A Couples-focused Intervention for HIV Prevention and Care in South Africa

From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing (intervention arm) or an attention matched control. The research examines the impact of a package …

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women

in sub-Saharan Africa. Informed, Motivated, Aware, and Responsible Adolescents and Adults (IMARA) is an evidence-based HIV-prevention intervention for adolescent girls and young women (AGYW) and

Accepts healthy volunteers
AIDS
hiv test
pre-exposure prophylaxis (prep)
HIV Vaccine
  • 0 views
  • 04 Oct, 2022
  • 1 location
PrEParing Family Planning Clinics to Streamline Integration of HIV Prevention Services for Young Women in Kenya

This a prospective, open-label implementation project to catalyze integration of HIV prevention and PrEP care services for adolescent girls and young women in family planning clinics in Kenya

lamivudine
tenofovir
HIV Vaccine
emtricitabine
  • 0 views
  • 28 Sep, 2021
  • 1 location
Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

The purpose of this study is to evaluate the pharmacokinetics, feasibility, acceptability, and safety of a fixed-dose combination of emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) as oral daily pre-exposure prophylaxis (PrEP) to prevent HIV during pregnancy and postpartum in adolescents and young women and their infants.

drug levels
emtricitabine/ tenofovir disoproxil fumarate
drug level
acute hiv infection
HIV Vaccine
  • 142 views
  • 07 Oct, 2022
  • 6 locations
Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW (LifeSkills)

The LifeSkills Mobile app will be evaluated in a randomized controlled trial (RCT) among 5,000 young transgender women (YTW), ages 16-29 in the United States (U.S.). Study findings will demonstrate if the intervention will reduce HIV incidence.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Peer PrEP Referral + HIV Self-test Delivery for PrEP Initiation in Kenya (PeerPrEP)

Few young women at risk of HIV infection are initiating pre-exposure prophylaxis (PrEP) for HIV prevention in Kenya, thus we propose refining and testing a new model to increase PrEP initiation

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services (CoMPASS)

and support services (CoMPASS) to promote HIV prevention among individuals with opioid use disorder who inject drugs. In parallel, the investigators will conduct an implementation focused process

Accepts healthy volunteers
  • 0 views
  • 11 May, 2022
  • 4 locations
Clinic-based HIV Identification and Prevention Project Using Electronic Resources (CHIPPER)

Hybrid Type II effectiveness-implementation trial to investigate whether electronic medical and sexual history data collection with HIV risk categorization/scoring will increase pre-exposure prophylaxis (PrEP) uptake among cis-gender women attending routine well-woman gynecologic preventative visits.

Accepts healthy volunteers
  • 0 views
  • 28 Oct, 2022
Thetha Nami Ngithethe Nawe ("Let's Talk"): Step Wedge cRCT of Peer Led Community PrEP and SRH for Youth in South Africa

Study Hypothesis: Social mobilisation will attract and engage young people into decentralised sexual reproductive health (SRH) services where HIV prevention is tailored to need. Decentralised

antiretroviral
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Prevention of HIV in "Île-de-France" (ANRS-PREVENIR)

Interventional HIV prevention strategy based on pre-exposure prophylaxis (PrEP) with Truvada® for people in the Île-de-France area (or Paris region) who don't have HIV but who are at high risk

enzyme-linked immunosorbent assay
antiretroviral
truvada
post-exposure prophylaxis
hiv test
  • 5 views
  • 13 Jun, 2022
  • 2 locations