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Found 34 clinical trials
The Effectiveness of High Resolution Microendoscopy for People Living With HIV

The investigators have developed a portable, battery-operated, mobile high-resolution microendoscope (mHRME) that provides subcellular images of the anal epithelium, delineating the cellular and morphologic changes associated with neoplasia. The investigators' central hypothesis is that this 'optical' approach will increase the efficiency, clinical impact, and cost-effectiveness of the current standard of …

  • 22 views
  • 18 Sep, 2021
  • 1 location
Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients

Combined antiretroviral therapy (ART) efficiently suppresses viral replication and markedly decreases mortality among patients with HIV-1 infection/AIDS. While the advanced AIDS patients with CD4+T cell count less than 200 cells/L often develop seriously opportunistic infections (OIs), severe wasting syndrome, and other fatal complications, which are the major causes of death …

  • 0 views
  • 16 Feb, 2022
  • 1 location
Pomalidomide Treatment in Patients With Kaposi Sarcoma

This phase II trial studies the effect of pomalidomide in treating patients with Kaposi sarcoma. Pomalidomide is a cancer fighting drug that stops the growth of blood vessels, stimulates the immune system, and may kill cancer cells.

  • 0 views
  • 10 Mar, 2022
  • 2 locations
Financial Incentives, Randomization With Stepped Treatment Trial (FIRST)

The investigators plan to determine the effectiveness of contingency management (CM) plus stepped care for unhealthy alcohol use in HIV-positive patients.

  • 141 views
  • 13 Feb, 2022
  • 2 locations
Home-based Intervention to Test and Start (HITS)

This study aims to establish the causal impact of two interventions - micro-incentives and a male-sensitive HIV- specific decision support app - on population-level HIV viral load and HIV

hiv viral load
hiv test
Accepts healthy volunteers
HIV Vaccine
  • 1 views
  • 01 Feb, 2022
  • 1 location
Community Based Interventions to Improve HIV Outcomes in Youth: a Cluster Randomised Trial in Zimbabwe (CHIEDZA)

with sexual and reproductive health (SRH) services and general health counselling for 16 to 24 year olds on population level HIV viral load in a high HIV prevalence setting.

hiv viral load
hiv test
Accepts healthy volunteers
HIV Vaccine
  • 18 views
  • 15 Feb, 2022
  • 3 locations
Strategic Antiretroviral Therapy and HIV Testing for Youth in Rural Africa

The goal of this study is to evaluate the effect of a combination intervention on long-term HIV viral load (VL) suppression among HIV-infected adolescents and young adults 15-24 years of age

HIV Infection
hiv viral load
HIV Vaccine
hiv test
antiretroviral agents
  • 0 views
  • 04 Feb, 2022
  • 2 locations
Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal

Despite advances in efficacious, efficient and safe biomedical tools to reduce HIV transmission and acquisition the HIV epidemic in South Africa(SA) remains an intractable problem, with the lifetime risk of infection approaching 70% for a 15-year-old girl currently living in northern KwaZulu-Natal, the Africa Health Research Institute(AHRI) research setting. This …

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location
Improving Maternal heAlth by Reducing Malaria in African HIV Women (MAMAH)

Trial to evaluate the safety and efficacy of DHA-PPQ for Intermittent Preventive Treatment (IPTp) in HIV-infected pregnant women receiving cotrimoxazole prophylaxis (CTXp) and antiretroviral (ARV) drugs and using long lasting insecticide treated nets will be conducted in Mozambique and Gabon where malaria and HIV infection are moderate to highly prevalent. …

HIV Infection
piperaquine
Accepts healthy volunteers
dihydroartemisinin
antiretroviral agents
  • 0 views
  • 20 Feb, 2022
  • 1 location
Contingency Management for Cannabis Use for Persons With HIV

withdrawal, HIV viral load and biomarkers of systemic inflammation among PLWH and who use cannabis regularly (weekly or more often). This will be a single arm pilot feasibility trial involving a contingency

hiv viral load
HIV Vaccine
  • 0 views
  • 15 Mar, 2022
  • 1 location