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Found 30 clinical trials
The Effectiveness of High Resolution Microendoscopy for People Living With HIV

The investigators have developed a portable, battery-operated, mobile high-resolution microendoscope (mHRME) that provides subcellular images of the anal epithelium, delineating the cellular and morphologic changes associated with neoplasia. The investigators' central hypothesis is that this 'optical' approach will increase the efficiency, clinical impact, and cost-effectiveness of the current standard of …

  • 22 views
  • 18 Sep, 2021
  • 1 location
Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients

Combined antiretroviral therapy (ART) efficiently suppresses viral replication and markedly decreases mortality among patients with HIV-1 infection/AIDS. While the advanced AIDS patients with CD4+T cell count less than 200 cells/L often develop seriously opportunistic infections (OIs), severe wasting syndrome, and other fatal complications, which are the major causes of death …

  • 0 views
  • 16 Feb, 2022
  • 1 location
A Multicenter Phase II Study of Pomalidomide Monotherapy in Kaposi Sarcoma

This phase II trial studies the effect of pomalidomide in treating patients with Kaposi sarcoma. Pomalidomide is a cancer fighting drug that stops the growth of blood vessels, stimulates the immune system, and may kill cancer cells.

  • 0 views
  • 27 Oct, 2022
  • 2 locations
Home-based Intervention to Test and Start (HITS)

This study aims to establish the causal impact of two interventions - micro-incentives and a male-sensitive HIV- specific decision support app - on population-level HIV viral load and HIV

Accepts healthy volunteers
hiv test
HIV Vaccine
hiv viral load
  • 1 views
  • 01 Feb, 2022
  • 1 location
Strategic Antiretroviral Therapy and HIV Testing for Youth in Rural Africa

The goal of this study is to evaluate the effect of a combination intervention on long-term HIV viral load (VL) suppression among HIV-infected adolescents and young adults 15-24 years of age

antiretroviral agents
hiv test
HIV Vaccine
antiretroviral therapy
hiv viral load
  • 0 views
  • 04 Oct, 2022
  • 2 locations
PEER Trial: Part 2

The study aims to compare the accuracy of the lateral flow test to detect HPV at the POC with the commercially available GeneXpert HPV test and to determine the diagnostic accuracy and reliability of a multimodal optical imaging system to detect cervical dysplasia, with the gold reference standard of histopathology.

cervical dysplasia
cancer screening
cervical cancer screening
hpv test
colposcopy
  • 0 views
  • 04 Jul, 2022
  • 4 locations
Prevention of HIV in "Île-de-France" (ANRS-PREVENIR)

Interventional HIV prevention strategy based on pre-exposure prophylaxis (PrEP) with Truvada® for people in the Île-de-France area (or Paris region) who don't have HIV but who are at high risk of becoming infected with HIV (men who have sex with men (MSM), transgender men and women, heterosexual men and women, …

pre-exposure prophylaxis (prep)
antiretroviral agents
hepatitis
gonorrhea
venereal disease
  • 5 views
  • 13 Jun, 2022
  • 2 locations
Thetha Nami Ngithethe Nawe ("Let's Talk"): Step Wedge cRCT of Peer Led Community PrEP and SRH for Youth in South Africa

Study Hypothesis: Social mobilisation will attract and engage young people into decentralised sexual reproductive health (SRH) services where HIV prevention is tailored to need. Decentralised risk informed (differentiated) biosocial HIV prevention will reduce the overall prevalence of sexually transmissible HIV amongst young people aged 15-30. Study aims: Measure the impact …

Accepts healthy volunteers
antiretroviral
  • 0 views
  • 04 Oct, 2022
  • 1 location
Contingency Management for Cannabis Use for Persons With HIV

withdrawal, HIV viral load and biomarkers of systemic inflammation among PLWH and who use cannabis regularly (weekly or more often). This will be a single arm pilot feasibility trial involving a contingency

HIV Vaccine
hiv viral load
  • 0 views
  • 15 Mar, 2022
  • 1 location
Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals (YF-HIV)

neutralizing antibodies are associated with CD4 lymphocyte counts, CD8 lymphocyte counts, CD4 nadir, HIV viral load and use of antiretroviral therapy. To assess the yellow fever vaccine viremia at day 10 after

antiretroviral agents
vaccination
Accepts healthy volunteers
antiretroviral therapy
antiretroviral
  • 6 views
  • 25 Feb, 2022
  • 1 location