Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 7 clinical trials
CD4 CAR+ ZFN-modified T Cells in HIV Therapy

This research study is being carried out to study a new way to possibly treat HIV. As part of this study, doctors will take some of your own white blood cells, called T-cells, and modify them so that they can identify and target your HIV cells. The purpose of the …

hepatitis b surface antigen
antiretroviral agents
hepatitis
white blood cell count
leukapheresis
  • 27 views
  • 27 Jan, 2021
  • 1 location
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

The study hypothesis is to determine the feasibility of switching HIV-HCV co-infected patients receiving methadone or buprenorphine/naloxone as opioid substitution therapy with suppressed HIV RNA viral load on current antiretroviral therapy to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF, Genvoya) followed by 12 weeks of HCV antiviral therapy with sofosbuvir/velpatasvir (SOF/VEL, Epclusa), followed then …

antiretroviral agents
antiretroviral
velpatasvir
opioid
tenofovir
  • 67 views
  • 23 Jan, 2021
  • 1 location
EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

bone marrow biopsy is repeated after cycle 2 if a biopsy was initially positive on screening for participation in the study. Anti-HIV therapy is stopped before chemotherapy begins and is

hodgkin's disease
rituximab
etoposide
b-cell lymphoma
vincristine
  • 18 views
  • 26 Jan, 2021
  • 1 location
Maraviroc to Augment Rehabilitation Outcomes After Stroke

After stroke, the combination of progressive skills practice in an adequate dose, exercise for fitness, and reduced sedentary time will augment motor and cognitive outcomes. Sensorimotor and cognitive improvements after stroke often reach a general plateau by approximately 12 weeks after onset, however. Drugs that might enhance learning or neural …

rehabilitation therapy
infarct
stroke rehabilitation
hemiparesis
  • 61 views
  • 23 Jan, 2021
  • 3 locations
German Centre for Infection Research HIV Translational Platform

Despite major advances in therapy and management, HIV/AIDS continues to be a major cause of infectious disease morbidity and mortality on a global scale. The discovery of effective antiretroviral treatment has turned HIV infection into a manageable chronic disease in most patients with access to care. However, the different economic …

antiretroviral agents
HIV Vaccine
HIV Infection
chronic disease
AIDS
  • 13 views
  • 21 Jan, 2021
  • 1 location
Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care

This study aims to evaluate two ways to help people re-engage with healthcare. The first is to assess if providing HIV treatment on the first visit (or within 1 week) can help people re-engage with care and ultimately stay in care after 24 and 48 weeks. It will also assess …

HIV Vaccine
HIV Infection
  • 0 views
  • 24 Jan, 2021
  • 2 locations
A Surveillance Program for the Detection of Hepatitis B Virus (HBV) Resistance to Tenofovir in HIV-HBV co-Infected Patients

Human immunodeficiency virus/Hepatitis B virus (HIV/HBV) co-infections are frequently observed due to shared routes of transmission, with reported figures indicating 6-9% of HIV-infected individuals in developed countries are chronically infected with HBV. HIV infection impacts on the natural progression of HBV infection, increasing levels of HBV replication and the risk …

hepatitis
immunodeficiency
antiviral drugs
tenofovir
  • 6 views
  • 07 Nov, 2020
  • 1 location