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Found 8 clinical trials
Imaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment Interruption

Background Human immunodeficiency virus (HIV) infects CD4 T cells. There is no cure for HIV. People with HIV need to take daily medications called antiretroviral therapy (ART) to control their infection. ART stops HIV from infecting cells, but HIV does not go away. Some infected cells remain. If ART is …

  • 0 views
  • 26 Jul, 2022
  • 1 location
Impact of Metformin on Immuno-virologic Parameters in HIV

checkpoint receptors, plasma indoleamine 2,3-dioxygenase (IDO) levels and CD4 T cell and monocyte intracellular HIV DNA and HIV RNA. The study will also explore the 72 week impact of metformin on change in

antiretroviral agents
antiretroviral therapy
hiv dna
  • 0 views
  • 24 Jan, 2021
Triple vs. Double Therapy in na ves HIV-Infected Patients

activation of monocytes/ macrophages and plasma concentrations of various inflammatory mediators by ELISAS, and the thymic function, the cellular reservoir of HIV and the degree of HIV DNA transcription by

antiretroviral agents
dolutegravir
antiretroviral
hormonal contraception
hiv dna
  • 0 views
  • 25 Jan, 2021
  • 1 location
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients (GALIG-CBD)

Autophagy and apoptosis are natural cellular mechanisms which consist for the first in a recycling and elimination process of potentially toxic cellular waste, and for the second in a process of cellular suicide when it becomes abnormal and "not" repairable, notably by autophagy. A deficit in autophagic function at the …

  • 0 views
  • 08 Jul, 2022
Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS Patients

Opportunistic fungal infection is the most common opportunistic infection in AIDS patients, with the high mortality and recurrence rate due to the lack of standardized comprehensive diagnosis and treatment strategy. This project aims to combine traditional detection and observation indicators with molecular biology, serology and mass spectrometry identification technology to …

  • 0 views
  • 24 Dec, 2021
  • 1 location
HIV-DNA Dynamics in HIV Monoinfected or HIV/HCV Coinfected Patients (ViDyMoCo)

New markers of viral activity are now under investigation. Aim of the study is to investigate the efficacy of new antiretroviral drugs by monitoring HIV-DNA dynamics in HIV-positive population

antiretroviral agents
HIV Vaccine
antiviral drugs
  • 51 views
  • 24 Feb, 2022
  • 1 location
Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy

selective pressure. There is a need to assess the dynamic of archived Drug resistance associated mutations (DRAMs) clearance in cell-associated HIV DNA after a long period of virological control, in

  • 0 views
  • 31 Jul, 2021
  • 1 location
Observational Study for the Evaluation of the Role of HIV-1 Tat Protein and Anti-Tat Immune Response In HIV Reservoir (ISS OBS T-005)

A longitudinal observational study in HIV-infected subjects receiving cART addressed to explore the effect of the Tat protein and anti-Tat immunity on the formation and maintenance of HIV-1 virus reservoir.

  • 0 views
  • 05 Apr, 2022
  • 1 location