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Found 55 clinical trials
Study of Lenalidomide/Rituximab Maintenance for Transplantation Ineligible Patients With PCNSL. (Lemon-C)

>Consolidation therapy after induction therapy includes whole-brain radiation therapy, high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-SCT), and high

  • 0 views
  • 24 Mar, 2022
  • 1 location
ChiCGB vs BEAM in High-risk or R/R Lymphomas

High-dose chemotherapy (HDT) with autologous stem cell transplantation (ASCT) plays a vital role in treating high-risked or relapsed/refractory lymphoma. Our previous study showed chidamide

renal function
carbon monoxide
etoposide
ejection fraction
stem cell transplantation
  • 0 views
  • 04 Oct, 2022
  • 7 locations
Oral Supplementation of 2'-Fucosyllactose in Allogeneic Bone Marrow Transplant Recipients

High dose chemotherapy and radiation used as preparative regimens in patients undergoing an allogeneic hematopoietic stem cell transplant (HSCT) disrupts intestinal homeostasis by damaging the

acute graft-versus-host disease
graft versus host disease
allogeneic hematopoietic stem cell transplant
bone marrow transplant
  • 0 views
  • 13 Jun, 2022
  • 1 location
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases

which might include the brain/spinal cord and/or the peripheral nerves. Giving high-dose chemotherapy, including carmustine, etoposide, cytarabine, melphalan, and antithymocyte globulin, before a

anna-1
MRI
antithymocyte globulin
cerebellar degeneration
polyradiculoneuropathy
  • 214 views
  • 11 Jul, 2022
  • 3 locations
Safety and Tolerability of Intravenous Fish Oil Lipid Emulsion in Children Undergoing Hematopoietic Cell Transplantation

-dose chemotherapy and/or radiation-related toxicity. Parenteral nutrition (PN) with lipid emulsion is commonly required while gastrointestinal complications preclude adequate oral or enteral intake. PN

nutritional care
myelodysplasia
hematologic malignancy
transplant conditioning
hematologic disorder
  • 8 views
  • 29 Jun, 2022
  • 1 location
A Phase 2 Trial of Chemotherapy Followed by Response-Based Whole Ventricular &Amp; Spinal Canal Irradiation (WVSCI) for Patients With Localized Non-Germinomatous Central Nervous System Germ Cell Tumor

brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side

platelet count
gonadotropin
immature teratoma
alpha fetoprotein
brain tumor
  • 0 views
  • 19 Aug, 2022
  • 35 locations
Autologous Stem Cell Transplant for Crohn's Disease

undergo stem cell transplant which will involve high dose chemotherapy and require a 2-4 week hospitalization. After restoration of the immune system patients will be placed on vedolizumab per standard

tumor necrosis factor
golimumab
certolizumab pegol
enteropathy
ustekinumab
  • 82 views
  • 04 Oct, 2022
  • 1 location
Reduced Intensity Transplantation for Severe Sickle Cell Disease

This study is being done to test a transplant method that may have fewer side effects (or less toxic, less harmful) than conventional high dose chemotherapy conditioning-based transplants for

hydroxyurea
splenic sequestration
cerebral blood flow
plerixafor
hemoglobinopathy
  • 0 views
  • 29 May, 2022
  • 1 location
Copanlisib With Rituximab-Bendamustine in Patients With Relapsed-Refractory Diffuse Large B-cell Lymphoma

This is a multicentric single arm phase II trial, to investigate the efficacy (in terms of PFS) of the combination regimen rituximab-bendamustine in association with copanlisib in patients affected by relapsed/refractory DLBCL, not eligible to HDC and ASCT or relapsed after intensified regimens.

  • 0 views
  • 16 May, 2022
  • 14 locations
R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL a Multicenter Phase Ib/II Stuty

This is a multicenter prospective single arm phase Ib/II study, and the purpose of this study is to evaluate the safety and efficiency of R2-MTX regimen (rituximab & lenalidomide & methotrexate) combined with lenalidomide maintenance in newly-diagnosed primary central nervous system lymphoma. 2-year Progression free survival (PFS) of the cohort …

nervous
rituximab
methotrexate
lenalidomide
  • 0 views
  • 24 Jan, 2021
  • 1 location