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Found 53 clinical trials
Music Therapy For The Treatment Of Cisplatin Induced Tinnitus In Patients With rGCC: A Pilot Study

Pilot study evaluating the feasibility of recruitment, retention, and compliance to a modified Heidelberg Model of Neuro-Music Therapy (mHNMT) in patients with Cisplatin-induced Tinnitus and relapsed Germ Cell Cancer (rGCC).

  • 0 views
  • 01 Jul, 2022
  • 1 location
R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL a Multicenter Phase Ib/II Stuty

This is a multicenter prospective single arm phase Ib/II study, and the purpose of this study is to evaluate the safety and efficiency of R2-MTX regimen (rituximab & lenalidomide & methotrexate) combined with lenalidomide maintenance in newly-diagnosed primary central nervous system lymphoma. 2-year Progression free survival (PFS) of the cohort …

lenalidomide
rituximab
methotrexate
nervous
  • 0 views
  • 24 Jan, 2021
  • 1 location
Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

Clinical Study on the Safety and Effectiveness of Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

remission
granulocyte colony stimulating factor
follicular lymphoma
cell transplantation
lymphoma
  • 0 views
  • 24 Mar, 2022
  • 1 location
Chemotherapy and G-CSF for Mobilization (MOCCCA)

This study aims to demonstrate that the mobilization with cytokine stimulation with G-CSF alone is non-inferior as compared to the standard mobilization with chemotherapy and G-CSF while associated with fewer side effects in myeloma patients.

granulocyte colony stimulating factor
chemotherapy regimen
filgrastim
colony stimulating factor
melphalan
  • 4 views
  • 26 Feb, 2022
  • 1 location
A Study of Isatuximab Added to Standard CyBorD Induction and Lenalidomide Maintenance Treatments in ND-TEMM

This is a phase II multi-center, open label, single arm study to evaluate the safety and efficacy of Isatuximab administered intravenously in combination with CyBorD induction treatment and Lenalidomide maintenance treatment in a 28-day long cycle in autologous stem cell transplant-eligible patients.

lenalidomide
  • 0 views
  • 11 Mar, 2022
  • 5 locations
Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old

A phase I-II trial based on the combination of three drugs regimen LDAC or Azacitidine + Venetoclax + Quizartinib that in this population could be well tolerated by a sequential type administration. The first objective is to achieve rapid control of the disease, using two different schemes, one based in …

cytarabine
azacitidine
venetoclax
ejection fraction
  • 0 views
  • 25 May, 2021
  • 15 locations
Heated Intraperitoneal Chemotherapy in Primary Ovarian Cancer Patients

This study will evaluate the use of Heated Intraperitoneal Chemotherapy (HIPEC) for primary treatment of ovarian cancer at the time of surgical debulking, to assess if intravenous (IV) chemotherapy can be started within 42 days of HIPEC and cytoreduction. All patients will receive cytoreductive surgery followed by a one-time closed …

clear cell adenocarcinoma
carcinoma
cytoreductive surgery
tumor debulking
cancer chemotherapy
  • 12 views
  • 25 Mar, 2022
  • 1 location
Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis

The purpose of this trial is to compare the morbidity and mortality of CRS-HIPEC using mitomycin-C versus melphalan for colorectal peritoneal carcinomatosis. Morbidity and mortality will measured using the Comprehensive Complication Index (CCI) score, Common terminology criteria for adverse events (CTCAE version 4.03), and the Clavien-Dindo Classification.

metastasis
neutrophil count
systemic chemotherapy
mitomycin
hyperthermic intraperitoneal chemotherapy
  • 67 views
  • 17 Jun, 2022
  • 1 location
Olanzapine for Nausea/Vomiting Prophylaxis in Recipients of Hematopoietic Stem Cell Transplants

The purpose of this research study is to see if olanzapine helps to prevent nausea and/or vomiting (throwing up) when it is added to other medicines in subjects having stem cell transplants. Subjects will either be given olanzapine or an inactive pill (called a placebo) before getting any chemotherapy that …

  • 0 views
  • 28 Nov, 2021
  • 1 location
Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence

Most pediatric patients with solid tumors respond to initial high-dose, intensive therapy and complete treatment in remission. High-risk patients however, frequently have recurrent disease which is then treated with ad hoc regimens or early phase therapies with little benefit to the patient. Metronomic therapy (MC), defined as lower dose continuous …

sarcoma
platelet count
blood transfusion
neutrophil count
kidney function test
  • 0 views
  • 21 Jan, 2021
  • 2 locations