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Found 53 clinical trials
Microbiome in Cancer Patients With High Dose Chemotherapy With Stem Cell Transplantation

Numerous in vitro and animal studies as well as growing number of clinical studies support the important role of microbiome in carcinogenesis and cancer treatment. Detection of changes in patients microbiome following hematopoietic cell transplantation/CAR-T cell therapy and correlations with adverse transplant outcomes, mainly infectious complications, acute and chronic GvHD, …

  • 0 views
  • 13 Mar, 2021
  • 1 location
Blinatumomab Followed by High-dose Chemotherapy for Ph-negative Acute Lymphoblastic Leukemia (ALL) (Blina-CELL)

This is a phase II interventional trial to evaluate the efficacy of blinatumomab followed by high-dose chemotherapy in the first-line treatment for Ph-negative acute lymphoblastic leukemia (ALL

  • 0 views
  • 06 May, 2022
  • 2 locations
Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

This phase I trial studies the side effects and best dose of olaparib when given together with high-dose chemotherapy in treating patients with lymphomas that have come back or does not

high-dose chemotherapy
tumor cells
rituximab
monoclonal antibodies
serum pregnancy test
  • 2 views
  • 03 May, 2022
  • 1 location
A Study of the Effects of AB-205 in Patients With Lymphoma Undergoing Autologous Hematopoietic Cell Transplantation (E-CELERATE)

High-dose chemotherapy followed by blood stem cell transplantation is administered to lymphoma patients with an intention to cure. However, high-dose chemotherapy simultaneously causes damage to

cell transplantation
etoposide
lymphoma
carmustine
high dose chemotherapy
  • 0 views
  • 26 May, 2022
  • 5 locations
  • 0 views
  • 11 Feb, 2022
  • 1 location
Autologous Stem Cell Transplantation for Crohn's Disease

The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC

ustekinumab
crohn's disease
stem cell transplantation
mercaptopurine
cyclophosphamide
  • 168 views
  • 21 Mar, 2022
  • 2 locations
Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem

high-dose chemotherapy
ifosfamide
tumor markers
bleomycin
human chorionic gonadotropin
  • 0 views
  • 08 Mar, 2022
  • 1 location
  • 0 views
  • 27 Jan, 2021
  • 1 location
Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias

The purpose of this study is to evaluate the safety and efficiency of personalized targeted therapy in combination with high-dose chemotherapy as part of a preparative regimen before T-depleted

  • 0 views
  • 26 Jan, 2021
  • 1 location
Study of Lenalidomide/Rituximab Maintenance for Transplantation Ineligible Patients With PCNSL. (Lemon-C)

>Consolidation therapy after induction therapy includes whole-brain radiation therapy, high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto-SCT), and high

  • 0 views
  • 24 Mar, 2022
  • 1 location