Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 40 clinical trials
The WWRD Study: AVM0703 for Treatment of Leukemia or Lymphoma

This is an open-label, Phase 1/2 study designed to characterize the safety, tolerability, Pharmacokinetics(PK), and preliminary antitumor activity of AVM0703 administered as a single intravenous (IV) infusion to patients with lymphoid malignancies.

  • 7 views
  • 15 Mar, 2022
  • 5 locations
GEN3013 Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

The trial is an open-label, multi-center safety trial of epcoritamab GEN3013 (DuoBody-CD3xCD20). The trial consists of two parts: a dose escalation part phase 1, first-in-human (FIH) and an expansion part phase 2a.

combination chemotherapy
pet/ct scan
renal function
renal function tests
cell transplantation
  • 324 views
  • 12 Feb, 2022
  • 65 locations
First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas

The drug that will be investigated in the study is an antibody, GEN3009. Since this is the first study of GEN3009 in humans, the main purpose is to evaluate safety. Besides safety, the study will determine the recommended GEN3009 dose to be tested in a larger group of patients and …

btk inhibitor
cancer
measurable disease
refractory b-cell non-hodgkin lymphoma
leukemia
  • 17 views
  • 25 Mar, 2022
  • 14 locations
R-BL-M-04 Versus R-(DA)-EPOCH and Autologous Stem Cells Transplantation in Patients With High-Grade B-cell Lymphoma Double-hit (HGBL DH) and High-Grade B-cell Lymphoma Not Otherwise Specified (HGBL NOS)

with High-Grade B-cell Lymphoma Double-hit and High-Grade B-cell Lymphoma Not Otherwise Specified.

cell transplantation
diffuse large b-cell lymphoma
b-cell lymphoma
  • 34 views
  • 01 Mar, 2022
  • 1 location
Copanlisib With Dose-Adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and Other High-Grade B-cell Lymphomas

Background Burkitt Lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) are aggressive B cell lymphomas. Frontline treatment does not always work. Researchers want to see if a combination of drugs can help. Objective To learn if it is safe to give people with certain cancers copanlisib together with rituximab and …

cyclophosphamide
prednisone
diffuse large b-cell lymphoma
vincristine
cancer chemotherapy
  • 0 views
  • 16 May, 2022
  • 1 location
A Study of CPI-613 for Patients With Relapsed or Refractory Burkitt Lymphoma/Leukemia or High-Grade B-Cell Lymphoma With High-Risk Translocations

The purpose of this study is to test any good and bad effects of the study drug, CPI-613.

bone marrow procedure
cancer
measurable disease
leukemia
thrombocytopenia
  • 38 views
  • 05 Feb, 2022
  • 10 locations
Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Double or Triple Hit Lymphoma

This phase II trial studies how well polatuzumab vedotin and combination chemotherapy work in treating patients with previously untreated double or triple hit lymphoma. Polatuzumab vedotin is a monoclonal antibody that works by binding with cancer cells and releasing another chemotherapy drug, called monomethyl auristatin E, into the cell causing …

cancer
measurable disease
cyclophosphamide
platelet count
prednisolone
  • 0 views
  • 22 Mar, 2022
  • 2 locations
FT596 With Rituximab as Relapse Prevention After Autologous HSCT for NHL

transplant (auto-HSCT) for diffuse large or high-grade B cell lymphoma.

rituximab
b-cell lymphoma
remission
  • 0 views
  • 22 Mar, 2022
  • 1 location
  • 0 views
  • 06 May, 2022
  • 13 locations
A Multicenter Clinical Study on the Safety and Efficacy of CAR-T in the Treatment of Relapsed / Refractory Non Hodgkin's Lymphoma

, invasive lymphoma and inert lymphoma; Highly invasive NHL included Burkitt lymphoma (BL), lymphoblastic lymphoma (LBL), high-grade B-cell lymphoma, etc; Invasive NHL includes diffuse large B-cell lymphoma

  • 0 views
  • 27 Jan, 2021
  • 1 location