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Found 41 clinical trials
Featured trial
A Multiple-Dose, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3041658 in Patients with Neutrophilic Skin Diseases

A Multiple-Dose, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3041658 in Patients with Neutrophilic Skin Diseases

  • 574 views
  • 25 Mar, 2021
  • 1 location
A Study of Bermekimab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa (LYRA)

The purpose of this study is to evaluate the dose-response of bermekimab efficacy in participants with moderate to severe Hidradenitis Suppurativa (HS).

adalimumab
abscess
  • 124 views
  • 04 May, 2022
  • 38 locations
Creation of a Prospective Cohort of Healthy and Sick Subjects and of a Collection of Associated Biological Resources, for the Study of the Immune System and of Its Genetic and Environmental Determinants. (CoSImmGEn)

CoSImmGEn is a protocol set up to respond to the current lack of healthy and sick population cohorts. Biological resources from these cohorts allow researchers to study the immune system and its genetic and environmental determinants. Those cohorts and collections are open not only to the Pasteurian community but also …

Accepts healthy volunteers
  • 109 views
  • 04 Feb, 2022
  • 3 locations
Optimizing Intralesional Triamcinolone Dosing for Hidradenitis Suppurativa

Currently, there is limited evidence showing increased resolution of HS flares with higher doses of intralesional triamcinolone (ILTAC) as well as a difference in side effect profile between the doses. The goal of this study is to determine the efficacy of treating HS flares with ILTAC-10, ILTAC-20 and ILTAC-40 and …

abscess
triamcinolone
Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
Molecular Characteristics of Brodalumab in Hidradenitis Suppurativa

Hidradenitis suppurativa is a disease involving skin folds, causing swelling of the skin and surrounding tissues, pain, and foul-smelling discharges. Effective treatment options are lacking

  • 20 views
  • 02 Sep, 2021
  • 1 location
Intralesional Diode Laser Treatment of Fistulas in Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a common chronic skin disease where patients experience inflamed painful nodules and chronic suppurating tunnels under the skin that often leave mutilating scars

purulent discharge
anxiety
dmsc
  • 19 views
  • 09 Aug, 2021
  • 1 location
Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep

Izokibep is a potent and selective inhibitor of interleukin 17A (IL-17A) that is being developed for treatment of hidradenitis suppurativa (HS). This study will evaluate the efficacy

  • 0 views
  • 13 May, 2022
  • 3 locations
ATI-450 vs Placebo in Patients With Moderate to Severe Hidradenitis Suppurativa (HS)

This is a Phase 2a study to investigate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of ATI-450 vs placebo in patients with moderate to severe Hidradenitis

  • 0 views
  • 14 Mar, 2022
  • 3 locations
Study of the Effect of Fostamatinib Upon Cutaneous Inflammation in the Setting of Hidradenitis Suppurativa

A 16 week exploratory, Proof of Concept study to evaluate the effect of Fostamatinib (12 weeks of treatment) upon cutaneous inflammation in Hidradenitis Suppurativa.

  • 0 views
  • 27 Apr, 2022
  • 1 location
Study of Efficacy and Safety of Investigational Treatment in Patients With Hidradenitis Suppurativa

This is a randomized, double-blind, placebo-controlled, parallel-group phase 1b study to evaluate AT193 in approximately 44 participants with HS. The treatment period will be 8 weeks followed by a 2-week nontreatment follow-up. The primary objective of this study is to evaluate the safety and tolerability of AT193. The secondary objectives …

  • 0 views
  • 06 May, 2022
  • 7 locations