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Found 267 clinical trials
Imaging of Arthropathy in Boys With Hemophilia in China

Hemophilia is a genetic condition characterized by marked phenotypic heterogeneity. Bleeding into a joint is the single most important risk factor for the development of hemophilic arthropathy

antihemophilic factor
arthropathy
  • 3 views
  • 26 Jan, 2021
  • 1 location
PINPOINT: Gaming Technology for SCD Pain

Sickle cell disease (SCD) is a common genetic disorder characterized by episodes of pain, yet programs to assist SCD adolescents with better identification and communication about pain are

genetic disorder
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Realization of Sequencing of All Known Human Genes in Case of Detection of Cerebral Renal or Ophthalmological Fetal Malformations During Pregnancy in Order to Make an Etiological Diagnosis and to Precise the Fetal Prognosis

features as part of a syndromic condition. For some malformations strongly suggestive of a genetic condition, we propose to realize an exome (i.e. all coding parts of the genome) sequencing of the

  • 0 views
  • 26 Jan, 2021
  • 12 locations
Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants

SCID-X1 is a genetic disorder of blood cells caused by DNA changes in a gene that is required for the normal development of the human immune system. The purpose of this study is to determine if

  • 26 views
  • 28 Jan, 2021
  • 3 locations
Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.

Marfan syndrome (MFS) is a rare genetic disease (1/5000) characterized by the association of ocular impairment, cardiovascular disease and musculoskeletal disease. In some chronic

  • 5 views
  • 27 Jan, 2021
Epigenetic Regulation of Osteogenesis Imperfecta Severity : miROI Study

Osteogenesis Imperfecta (OI) is a heterogeneous group of rare connective tissue hereditary diseases responsible for fragility and bone deformity. OI is caused by an autosomal dominant mutation

autosomal dominant
bone disease
genetic disorder
col1a1
col1a2
  • 4 views
  • 23 Jan, 2021
  • 2 locations
Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta

Osteogenesis imperfecta (OI) is a rare genetic disorder of increased bone fragility and low bone mass. It is conceivable that children and adolescents with OI are less active than healthy peers

bone disease
genetic disorder
bone mineral density
  • 0 views
  • 27 Jan, 2021
  • 2 locations
Interventions for Reading Disabilities in NF1

Neurofibromatosis Type 1 (NF1) is a common genetic disorder that is associated with a four times greater risk of learning disabilities, including reading disabilities, and a deficiency of

deficiency
learning disability
lovastatin
stimulant
cerebral palsy
  • 113 views
  • 27 Jan, 2021
  • 1 location
Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy

inevitably premature death of affected young men in their late twenties. DMD is the most common fatal genetic disorder diagnosed in childhood. It affects approximately 1 in every 3,500 live male births

aldosterone
angiotensin
aldosterone antagonists
ace inhibitor
angiotensin converting enzyme
  • 3 views
  • 15 Feb, 2021
  • 6 locations
A Trial of Dabrafenib Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

mutations including BRAF V600 mutations or BRAF fusion/duplication, with or without neurofibromatosis type 1. Neurofibromatosis type 1 is an inherited genetic condition that causes tumors to grow on nerve

  • 4 views
  • 25 Jan, 2021
  • 13 locations