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Found 87 clinical trials
Feasibility of a New Technology for Isolating Circulating Tumour Cells

This is a prospective interventional single-site research with a collection of biological samples. The primary objective of the trial is to assess the ability of the "new technology" to isolating circulating tumor cells (CTC) in selected cancer patients. Five groups will be constitued: at first the Group 0: Healthy volunteers …

docetaxel
cancer antigen 125
cancer
HER2
breast cancer
  • 0 views
  • 20 Oct, 2021
  • 1 location
Efficacy and Safety of Sintilimab and Apatinib Combined Chemotherapy in Breast Cancer

The efficacy and safety of immunotherapy and antiangiotherapy in combination with chemotherapy in neoadjuvant therapy for triple-negative breast cancer (TNBC) were determined by the addition of sintilimab and apatinib to neoadjuvant chemotherapy To clarify the breast-conserving rate, toxicity, difference in pathologic complete response (pCR) rate of patients with PD-L1 (+) …

progesterone receptor
growth factor
EGFR
measurable disease
epidermal growth factor receptor
  • 0 views
  • 09 May, 2022
  • 1 location
Albumin-Bound Paclitaxel Combined With Antiangiogenic Agents in First-line Treatment of Relapsed or Metastatic TNBC

This is a prospective, randomized, open-label clinical study. 128 patients with relapsed or metastatic triple-negative breast cancer (TNBC) who had not been systematically treated are going to be enrolled and randomly assigned to 3 groups. Group A: albumin-bound paclitaxel (260mg/m2, intravenous infusion, once every 3 weeks). Group B: albumin-bound paclitaxel …

triple negative breast cancer
growth factor
measurable disease
mammogram
metastasis
  • 0 views
  • 07 Apr, 2022
  • 1 location
Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer

This phase II trial studies how well pembrolizumab works when given together with endocrine therapy and palbociclib in treating postmenopausal patients with newly diagnosed stage IV estrogen receptor positive breast cancer that has spread to other parts of the body (metastatic). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help …

palbociclib
treatment regimen
alopecia
breast cancer
liver metastasis
  • 99 views
  • 13 Apr, 2022
  • 7 locations
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video

Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women. This study will conduct a RCT to test the efficacy of a culturally-tailored theory-based video intervention aimed to address key psychosocial factors …

  • 0 views
  • 08 Dec, 2021
  • 1 location
GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients

More than three quarter of patients with breast cancer are treated by hormone pills called tamoxifen and aromatase inhibitors (AIs). AIs are drugs that stop female hormone production. This hormone production mostly happens in fat, muscle, and breast tissue in postmenopausal women. The female hormone estrogen is an important hormone …

breast cancer staging
tamoxifen
arimidex
HER2
anastrozole
  • 19 views
  • 13 May, 2022
  • 1 location
Tarlox and Sotorasib in Patients With KRAS G12C Mutations

This is a Phase IB dose expansion trial with safety lead-in evaluating the safety, clinical activity/efficacy of the combination of tarloxotinib and sotorasib in patients with KRAS G12C mutation who have progressed on any small molecule targeting KRAS G12C mutant Non-Small Cell lung cancer.

  • 0 views
  • 21 Apr, 2022
  • 1 location
Antler Plate on Preventing Mammary High-risk Lesions From Malignant Development

This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer

This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least

endoscopic biopsy
gastric adenocarcinoma
endoscopy
gastrectomy
adenocarcinoma
  • 0 views
  • 15 Dec, 2021
  • 1 location
Tumor-Infiltrating Lymphocytes and Programmed Cell Death - Ligand 1 in Breast Cancer

breast cancer (BC) lesions, TILs are seen in intratumoral and stromal areas. TILs are predictive of response to treatment and this association appears to be strongest in Triple-negative (TNBC) and Her 2

growth factor
EGFR
epidermal growth factor receptor
epidermal growth factor
immunohistochemistry
  • 0 views
  • 11 Mar, 2022
  • 1 location