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Found 13 clinical trials
The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations

Our study aims to evaluate the efficacy of intramyometrial injection of Terlipressin versus intramyometrial injection of Carbetocin on hemoglobin level in women undergoing abdominal myomectomy. Moreover, to evaluate their efficacy in decreasing blood loss on operative time and to describe the injection sequelae for the same population. This clinical study …

  • 4 views
  • 18 May, 2022
  • 2 locations
The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I

hepatorenal syndrome and to learn whether it has any effect on the blood circulation and kidney function.

ascites
glomerular filtration rate
dialysis
renal failure
renal replacement therapy
  • 0 views
  • 11 Jul, 2022
  • 1 location
Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) (INFUSE)

Hepatorenal syndrome-acute kidney injury (HRS-AKI), a potentially reversible renal failure, is a serious, rapidly progressing, often fatal, complication of decompensated cirrhosis. Terlipressin

ascites
aldosterone
angiotensin
renal failure
  • 0 views
  • 23 Apr, 2022
  • 7 locations
A Multi-Center, Randomized, Placebo-Controlled, Double-Blind, Adaptive Dose-Ranging Study to Assess Safety and Efficacy of Intravenous OCE-205 in Adults Diagnosed With Cirrhosis With Ascites Who Have Developed Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI)

OCE-205 is being tested to treat participants who have developed Hepatorenal Syndrome-Acute Kidney Injury as a complication of cirrhosis with ascites. The study aims are to evaluate the

ascites
hepatorenal syndrome
  • 0 views
  • 24 Oct, 2022
  • 12 locations
Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment (SHOT)

The purpose of this study is to evaluate whether statin could prevent recurrence of hepatocellular carcinoma after curative treatment

  • 43 views
  • 16 May, 2022
  • 5 locations
Single Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

This single ascending dose (SAD) study evaluates PHIN-214, being studied to determine the safety, tolerability, and pharmacokinetics, and establish the maximum tolerated dose of this compound in patients with compensated cirrhosis.

body mass index
fibroscan
terlipressin
  • 0 views
  • 07 Oct, 2022
  • 2 locations
Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)

This is an open-label, multi-center, randomized phase II study comparing the Y90 TARE followed by bevacizumab and atezolizumab treatment to the Y90 TARE treatment alone in unresectable advanced stage HCC.

anticoagulants
cancer
  • 0 views
  • 04 Oct, 2022
  • 6 locations
Microbiome and Sarcopenia in Patients With Liver Cirrhosis

Protein-energy malnutrition (PEM) occurs in 65-90% of patients with liver cirrhosis. Severity of malnutrition correlates with progression of liver disease and leads to sarcopenia in 30-70% of cirrhotic patients. Malnutrition and sarcopenia are associated with an increased risk of complications and mortality. In cirrhosis the gut microbiome is altered leading …

Accepts healthy volunteers
cirrhosis
malnutrition
liver disease
  • 8 views
  • 25 Feb, 2022
  • 1 location
International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project (GLOBAL-AKI)

The aims of this study will be to identify the clinical characteristics, the management and the outcomes of acute kidney injury in patients with cirrhosis worldwide. Specific aims: To establish the severity of AKI across different regions To identify precipitants of AKI across different centers To identify the phenotypes of …

ascites
vasopressor
liver disease
diuretics
encephalopathy
  • 0 views
  • 04 Oct, 2022
  • 34 locations
Real World Study of End-stage Liver Disease in China

The aims of this study are exploring the current situation of end-stage liver disease in China, and the optimization of diagnosis and treatment. Liver cirrhosis often accompanied by a series of complications. Therefore, it is necessary to standardize the diagnosis and treatment of liver cirrhosis and its complications. End-stage liver …

liver disease
hepatocellular carcinoma
liver failure
cirrhosis
carcinoma
  • 47 views
  • 14 Feb, 2022
  • 1 location