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Found 840 clinical trials
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging technique a person is laid in an MR scanner and a paddle (plastic drum) is put on the area of interest to send sound vibration via …

elastography
stiffness
MRI
  • 35 views
  • 25 Jan, 2021
  • 1 location
The Relationship Betweensarcopenia And Myosteatosis With The Natural History Of Liver Cirrhosis

Malnutrition is a common figure associated with liver cirrhosis. The main component of malnutrition in liver cirrhosis is represented by sarcopenia, a condition of a progressive and generalized loss of muscle mass and strength. Many studies have reported that sarcopenia is an independent predictor of morbidity and mortality in cirrhotic …

gastrointestinal hemorrhage
liver transplant
ascites
malnutrition
encephalopathy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Methacetin Breath Test in HCV Patients With Normal and Near-Normal ALT

A relatively large proportion of patients with chronic HCV infection have normal or mildly elevated ALT. Many of these patients are not being treated, and are not being sent for a liver biopsy. The present study will determine the ability of Methcetin BreathID Test(MBIT) to detect those patients who will …

  • 6 views
  • 07 Nov, 2020
  • 1 location
Alpha-1 Antitrypsin Deficiency Adult Liver Study

The investigators hypothesize that there is liver injury (inflammation, fibrosis, cirrhosis) in adults with Alpha-1 Antitrypsin Deficiency (AATD), which is asymptomatic, under-recognized, and undiagnosed. In addition, the investigators believe that the genetic and environmental factors that play an important role in the development of alpha-1 antitrypsin (AAT) liver disease, can …

cirrhosis
alpha1-proteinase inhibitor (human)
deficiency
liver injury
fibrosis
  • 232 views
  • 11 Mar, 2021
  • 3 locations
Use of Shear Wave Elastography to Assess Non-alcoholic Fatty Liver Disease (NAFLD)

The aim of this study is to test a non-invasive imaging technique to reliably diagnose NAFLD in children and adolescents with obesity and assess the degree of fibrosis.

shear wave elastography
fatty liver
elastography
fibrosis
liver disease
  • 1 views
  • 20 Mar, 2021
  • 1 location
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

The purpose of this study is to investigate the relationship between SDF-1/CXCR4 and metastasis of laryngeal and hypopharyngeal squamous cell carcinomas.

metastasis
carcinoma
squamous cell carcinoma
  • 2 views
  • 07 Nov, 2020
Pathophysiological Study of Adipose Tissue of Patients Infected With HIV

The main goal of our project is the study of subcutaneous and visceral (SAT and VAT) adipose tissue taken during bariatric surgery (Single port sleeve gastrectomy) of subjects with HIV infection, anf morbid obesity with undetectable viral load (VL) and having HIV lipohypertrophy particularly truncal. The study covers both the …

HIV Infection
hiv-1 infection
body mass index
HIV Vaccine
antiretroviral therapy
  • 3 views
  • 13 Feb, 2021
  • 1 location
Non-invasive Evaluation of Portal Hypertension in Patients With Compensated Advanced Chronic Liver Disease by Assessment of Spleen Stiffness Using Vibration Controlled Transient Elastography

Hypothesis: The severity of portal hypertension in compensated advanced chronic liver disease (cACLD) can be assessed using vibration controlled transient elastography (VCTE) via the FibroScan 502 Touch by measuring SS (splenic stiffness) Specific Aims: SS by VCTE will be measured in this single center clinical study comprising of 200 patients …

  • 0 views
  • 01 Feb, 2021
  • 1 location
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection

The purpose of this study is to examine gene expression profiles by DNA microarray in patients who are responders and non-responders to interferon and ribavirin treatment for hepatitis C virus (HCV). Genes involved in inflammation and fibrosis and mediators of the Th-1 lymphocyte response will be looked for. It is …

ribavirin
chronic hepatitis
interferon
mono
fibrosis
  • 47 views
  • 07 Nov, 2020
  • 1 location
Intervention to Hepatic and Pulmonary Metastasis in Breast Cancer Patients

The number of intervention performed for metastatic breast cancer has dramatically increased over the past 2 decades. Hepatectomy and pulmonary resection for stage IV colorectal cancer is now considered the standard of care for resectable patients with isolated hepatic and/or pulmonary disease and acceptable performance status. However, the indications for …

stage iv breast cancer
radiofrequency ablation
cancer
breast cancer
TACE
  • 214 views
  • 23 Jan, 2021
  • 1 location