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Found 842 clinical trials
Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection

PD1 blockade has been approved as salvage therapy for advanced hepatocellular carcinoma (HCC). Although there is not solid evidence that PD1 blockade would induce hepatitis B virus (HBV

  • 0 views
  • 27 Jan, 2021
  • 1 location
Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high

  • 38 views
  • 16 Feb, 2021
  • 6 locations
Clinical Study of VG161 in Subjects With Advanced Primary Liver Cancer

VG161 is a recombinant human-IL12/15/PDL1B oncolytic HSV-1 Injectable. This phase I study will be conducted in HSV-seropositive subjects with advanced primary liver cancer that are refractory to

  • 0 views
  • 30 Apr, 2021
  • 1 location
Toripalimab Combined With Donafenib in the Treatment of Advanced Hepatocellular Carcinoma

This study is an open, multi-center phase I/II clinical study.

  • 0 views
  • 14 May, 2021
  • 1 location
  • 0 views
  • 02 Apr, 2021
  • 1 location
A Single-arm Open-label Multi-center Phase II Clinical Study to Evaluate the Safety and Efficacy of Toripalimab Injection (JS001) Combined With Bevacizumab as the First-line Therapy for Advanced Hepatocellular Carcinoma (HCC)

first-line therapy for advanced HCC The study will use safety/tolerability and ORR as the primary study objectives and indicators, and plans to enroll about 50-60 patients.

  • 0 views
  • 01 May, 2021
  • 1 location
4th Generation Chimeric Antigen Receptor T Cells Targeting Glypican-3

A Phase I Clinical Study of 4th generation Chimeric Antigen Receptor T Cells Targeting Glypican-3 ( CAR-GPC3 T Cells) in Patients with Advanced Hepatocellular Carcinoma

  • 0 views
  • 23 Jan, 2021
  • 1 location
Tislelizumab Neo-adjuvant Treatment for Resectable RHCC

This single-arm phase II clinical trial aimed to explore the efficacy and safety of Tislelizumab as neoadjuvant treatment for resectable RHCC patients

  • 0 views
  • 28 Jan, 2021
  • 1 location
A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With FOLFOX4 in Subjects With Advanced HCC Who Have Never Received Prior Systemic Treatment.

The study is being conducted to evaluate the efficacy and safety of SHR-1210 plus FOLFOX4 in subjects with advanced HCC who have never received prior systemic treatment compared to placebo plus

  • 0 views
  • 25 Jan, 2021
  • 1 location
DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

The primary objective of the trial is the safety and tolerability of administering a vaccine targeting the DNAJB1-PRKACA fusion kinase, in combination with nivolumab and ipilimumab in patients with unresectable or metastatic FLC and to assess the T-cell response.

  • 1 views
  • 06 Apr, 2021
  • 1 location