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Found 676 clinical trials
Characterization of the Platelet Inflammatory Response in NAFL and NASH

The primary objective of the study is to identify which features of platelet activation promote the inflammatory response that underlies the progression from NAFL to NASH. Therefore, the investigators plan: To characterize and compare the platelet inflammatory phenotype in NAFL vs NASH patients To study if and how the signaling …

  • 22 Mar, 2022
  • 1 location
Prevalence of HBV in Pregnancy

The most common mode of HBV transmission is materno-fetal transmission mainly during labor. This study aims to estimate the seroprevalence of HBV infection and the possible risk factors of HBV acquisition in pregnant women in Upper Egypt and to evaluate the predictive value of HBeAg and quantitative HBsAg as surrogate …

  • 21 Jul, 2022
  • 1 location
HCV Reinfection in in HIV/HCV-coinfected Patients Achieving SVR by Antiviral Therapy

Chronic hepatitis C virus (HCV) infection remains a health burden in people living with human immunodeficiency virus (HIV). Interferon (IFN)-based therapy is the treatment of choice for HCV infection for HIV coinfected patients in earlier years. However, the treatment responses are far from ideal and the treatment-emergent adverse events (AEs) …

  • 05 Mar, 2021
  • 7 locations
Gut Permeability and Bariatric-metabolic Surgery

Increased intestinal permeability and dysbiosis have been causally associated with NAFLD and NASH progression. However, to date, there are no systematic studies, on the effect of bariatric-metabolic surgery on intestinal permeability and dysbiosis in the context of NAFLD development.

  • 16 Mar, 2022
  • 1 location
Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS

Portal hypertension is the end-stage fatal complications of liver cirrhosis. Decompensated cirrhosis patients can pass through transjugular intrahepatic portosystemic shunt to effectively prevent bleeding and refractory ascites. However, the occurrence of hepatic encephalopathy and liver function failure, infection, bleeding again are main lethality postoperative complications after TIPS. The accurate TIPS …

varicose veins
portosystemic shunt
  • 05 Feb, 2022
  • 1 location
Pathophysiological Study of Adipose Tissue of Patients Infected With HIV (ObéVIH)

The main goal of our project is the study of subcutaneous and visceral (SAT and VAT) adipose tissue taken during bariatric surgery (Single port sleeve gastrectomy) of subjects with HIV infection, anf morbid obesity with undetectable viral load (VL) and having HIV lipohypertrophy particularly truncal. The study covers both the …

HIV Infection
HIV Vaccine
antiretroviral therapy
antiretroviral agents
  • 23 Feb, 2022
  • 1 location