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Found 674 clinical trials
Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer

This phase II trial studies the effect of nivolumab and ADI-PEG 20 before surgery in treating patients with liver cancer that can be removed by surgery (resectable). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Effectiveness of Liver Transplantation for Unresectable Colorectal Liver Metastasis; Pilot Study

Unlike hepatocellular carcinoma, liver transplantation in patients with liver metastasis from colorectal cancer is limited in only few centers. Previously, it was not generally implemented due

  • 0 views
  • 17 Sep, 2022
  • 1 location
Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. …

  • 38 views
  • 27 Apr, 2022
  • 7 locations
A Single Center Study of Donafenib Combined With PD-1 + TACE in the First-line Treatment of aHCC

This study is expected to recruit 30 patients with unresectable HCC who will be treated with Donafenib combined with PD-1 + TACE. During the study period, the tumor efficacy and resectability

  • 0 views
  • 14 Apr, 2022
Treatment of Patients With Advanced Solid Tumors With Oral Agent ORIN1001 and in Combination With Standard of Care.

breast cancer, hepatocellular carcinoma, metastatic prostate cancer, pancreatic cancer, ovarian cancer and non-small cell lung cancer. Dose expansion of ORIN1001 as a single agent or in

  • 0 views
  • 04 Oct, 2022
  • 1 location
EUS-Guided Choledochoduodenostomy Versus ERCP for Primary Biliary Decompression in Distal Malignant Biliary Obstruction

Malignant biliary obstruction commonly caused by pancreatic adenocarcinoma, cholangiocarcinoma and other etiologies like gallbladder carcinoma, hepatocellular carcinoma, lymphoma, and metastasis

  • 0 views
  • 26 Sep, 2021
  • 1 location
Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia

suggests that these group are at risk of gradual disease progression and development of hepatocellular carcinoma. Peginterferon eliminates the hepatitis B virus through immune regulation and induction of

  • 0 views
  • 23 Mar, 2022
  • 1 location
Sex Differences in Effectiveness of CBT on IBS Project 3 (U54_P3_CBT)

BGM mechanisms. Research performed by UCLA SCOR during previous funding has established an increased responsiveness of the CRF-Locus Coeruleus (LCC) system in female IBS subjects, suggesting

  • 0 views
  • 24 Mar, 2022
  • 1 location
Dual Energy CT as a Noninvasive Method to Screen for Gastroesophageal Varices

staging of hepatocellular carcinoma. Single-Energy CT (SECT) has relatively high accuracy in prospective studies for detection of any and large varices but is associated with suboptimal contrast

  • 0 views
  • 04 Oct, 2022
  • 1 location
Durvalumab Plus Tremelimumab Combination Immunotherapy With or Without Weekly Paclitaxel in Patients With Advanced Biliary Tract Carcinoma (BTC) After Failure of Platinum-based Chemotherapy (IMMUNO-BIL)

mg (cycle 1 to cycle 4) in combination with durvalumab 1,500 mg Q4W in hepatocellular carcinoma. Following these results, we have changed the tremelimumab 75 mg x 4 schedule for the 300 mg x 1

  • 2 views
  • 01 Feb, 2022
  • 16 locations