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Found 1365 clinical trials
Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B (ADAPT)

Multicenter, Prospective Open-label Single Arm Trial Chronic hepatitis B male and female adults on antiviral treatment for hepatitis B, without cirrhosis who are currently HBV DNA (-) and HBeAg

  • 0 views
  • 27 May, 2022
  • 9 locations
Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune Hepatitis (CAMARO)

Rationale: Current standard therapy of autoimmune hepatitis consists of a combination of prednisolone and azathioprine. However, a significant proportion of patients does not respond to, or is

remission
liver disease
prednisolone
mycophenolate
pseudocholinesterase
  • 32 views
  • 15 Jun, 2022
  • 14 locations
Reducing Vertical Transmission of Hepatitis B in Africa (REVERT-B)

Hepatitis B virus is an infection that can be easily transmitted from women to newborns at the time of delivery. Our objective is to identify novel options that are effective and safe in

tenofovir
prenatal
lamivudine
hepatitis
fumarate
  • 0 views
  • 11 Mar, 2022
  • 1 location
Effects of Plant Sterols and Stanols on Liver Inflammation

This study is a randomized, placebo-controlled, double blinded pilot study to assess the effect of consuming plant sterol or plant stanol esters (3 grams/day) for 6 months on ALT concentrations in subjects with elevated ALT concentrations, i.e. who are at risk to develop NASH.

  • 0 views
  • 17 Sep, 2021
  • 1 location
Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B

In the globe, about 33% (2 billion) of population has ever been infected with hepatitis B virus (HBV), and about 5% (350-400 million) were chronical HBV infection. In areas with high prevalence

  • 0 views
  • 07 Apr, 2022
Tacrolimus Versus Mycophenolate for Autoimmune Hepatitis Patients With Incomplete Response on First Line Therapy (TAILOR)

Rationale: The combination of azathioprine and prednisone is the first-line treatment for autoimmune hepatitis (AIH), a chronic inflammatory disease of the liver. Complete biochemical remission

  • 0 views
  • 22 Mar, 2022
  • 1 location
Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patients

A multiple-center, open-label, Phase II clinical trial to evaluate the safety and the efficacy of HLX10 in chronic hepatitis B patients.

chronic hepatitis
neutrophil count
hepatitis b antigen
  • 2 views
  • 04 Mar, 2022
  • 3 locations
Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:

The objective of this study is to identify immunological mechanisms that contribute to normalization of liver inflammation in chronic hepatitis B (CHB) patients starting the antiviral nucleoside

  • 0 views
  • 23 Jan, 2021
  • 1 location
  • 0 views
  • 02 Dec, 2021
  • 1 location
Effectiveness of Antiviral Treatment in Cirrhotic Patients With Low-level Hepatitis B Virus DNA Levels

Multicenter, Open-label, Randomized Controlled Trial Male and female adults with liver cirrhosis due to chronic hepatitis B virus infection who have low-level viremia and are beyond treatment

  • 0 views
  • 04 Jan, 2022
  • 5 locations