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Found 1315 clinical trials
An Integrative Model for Palliative Care in End-Stage Liver Disease

The purpose of this research study is to understand the impact of palliative care in ESLD on quality of life, emergency room or hospital visits, and on care provider burden, and to work to develop the best way to provide palliative care in ESLD.

cirrhosis
jaundice
liver disease
liver transplant
ascites
  • 0 views
  • 12 Jul, 2022
  • 1 location
Comparison Between LDCT With DL Recontruction and Standard Dose CT

This prospective study aims to perform intra-individual comparison of the image quality between low dose liver CT with deep learning reconstruction and standard dose liver CT with iterative reconstruction in patients with liver metastasis.

  • 0 views
  • 15 Jun, 2022
  • 1 location
Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Hepatic Tumors Research Consortium Initiative

There are limited data regarding the biology and treatment of relapsed/refractory hepatoblastoma (rrHBL). This project provides the infrastructure for acquisition of biological specimens, imaging, and correlative clinical data to facilitate biology studies and characterization of rrHBL. This registry will collect clinical, demographic, and pathological data, specimens (as available) and imaging …

  • 0 views
  • 21 Oct, 2022
  • 1 location
Rapid Breath-hold Quantitative Macromolecular Proton Fraction Imaging for Liver Fibrosis

Chronic liver disease is a major health problem worldwide. Liver fibrosis is a key feature in most chronic liver diseases. When identified early, liver fibrosis may be reversible. Currently, liver biopsy is the gold standard for the diagnosis of liver fibrosis. Liver biopsy; however, is invasive. Non-invasive diagnostic tools are …

fibrosis
liver disease
biopsy of liver
  • 0 views
  • 20 Dec, 2021
  • 1 location
Extubation Failure in Critically Ill Cirrhotic Patients. (FREELIVER)

Although a life-saving intervention, invasive mechanical ventilation (MV) prone to complications and side effects. Cirrhotic patients with a need of prolonged MV have a poor prognosis in ICU compared to general population of critically ill patients. The optimal time for weaning from MV and extubation is therefore a crucial objective. …

  • 0 views
  • 22 Mar, 2022
  • 1 location
A Single Center Real-world Study of Donafenib in the Treatment of Hepatocellular Carcinoma in Routine Clinical Practice

This trial is a single center observational real-world study. It is planned to include 300 patients with unresectable hepatocellular carcinoma (uHCC) treated with Donafenib. The purpose of the study was to observe the effectiveness and safety of Donafenib in the real world.

  • 0 views
  • 19 Apr, 2022
Evaluation of the Results of Simultaneous Pancreatic and Hepatic Resections for Metastatic Neuroendocrine Tumors. (ReSiPaTNE)

The indications for synchronous liver resection for metastatic neuroendocrine tumors of pancreatic origin remain debated and poorly described in the literature. The reported mortality of this type of simultaneous resection remains very high, especially when a cephalic duodenopancreatectomy is associated with a hepatic resection (up to 40%). The benefit in …

pancreatic resection
  • 0 views
  • 07 Oct, 2022
A Real-world Study of Camrelizumab Combined With Apatinib Mesylate in Unresectable Hepatocellular Carcinoma

To evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the treatment of unresectable hepatocellular carcinoma.

measurable disease
ct scan
cancer
  • 0 views
  • 07 Oct, 2022
The Role Of Circulating Tumor Cells As Markers Of Advanced Disease And Prognosis In HCC

Hepatocellular carcinoma (HCC) recurs in up to 60% of patients who undergo resection. Circulating tumor cells (CTC) have been advocated as promotors of the recurrence. However, their role as prognostic markers in the surgical setting is unclear. The aim of the present study has been to assess the association between …

  • 0 views
  • 23 Mar, 2021
  • 4 locations
The Detection of Small Early Liver Cancer With Natural History Follow up (SELINA)

The SELINA study will recruit 200 patients with cirrhosis and small HCC and 50 patients with HCC but without cirrhosis (most of whom are expected to have FLD). Blood, urine and liver tissue samples (where available) will be collected for laboratory analysis. In a subgroup of patients (N=80, around 64 …

cancer
  • 0 views
  • 07 Oct, 2022
  • 1 location