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Found 173 clinical trials
Featured trial
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

anemia
aplastic anemia
myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia studies
  • 172 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Alzheimer's Disease Research Center Clinic/Research Core

This study is interested to observe normal aging in the brain. This study asks: How does the brain change during normal aging? This study is looking for: Older people who are cognitively normal and live near Lexington, Kentucky.

Accepts healthy volunteers
  • 128 views
  • 25 Feb, 2022
  • 1 location
Featured trial
Migraine Study for Men or Women ages 18 to 65 Currently Using Triptans. (e.g., Almotriptan/Axert; Frovatriptan/Frova; Rizatriptan/Maxalt; Sumatriptan/Imitrex; Zolmitriptan/Zomig)

Migraine Study for Men or Women ages 18 to 65 Currently Using Triptans. (e.g., Almotriptan/Axert; Frovatriptan/Frova; Rizatriptan/Maxalt; Sumatriptan/Imitrex; Zolmitriptan/Zomig)

  • 406 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)

  • 974 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease

  • 153 views
  • 25 Mar, 2021
  • 1 location
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

as well and include: comorbid substance use, both non-fatal and fatal opioid overdose, HIV and Hepatitis C (HCV) testing results and risk behaviors, incarceration, quality of life, psychiatric

  • 160 views
  • 24 Mar, 2022
  • 16 locations
Identification and Validation of Noninvasive Biomarkers of the Diagnosis and Severity of NASH in Type 2 Diabetics (Quid-Nash)

Metabolic diseases of the liver are silent affections whose morbidity is important. About 70% of patients with type 2 diabetes (T2D) are concerned. Of these, 50% develop clinically significant lesions (including non-alcoholic steatohepatitis or NASH) as they are associated with an increased risk of complications; and 15% progress to severe …

Accepts healthy volunteers
  • 0 views
  • 09 Apr, 2022
  • 1 location
Twice Against Thrice-weekly Hemodialysis (TATH)

Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …

hypertension
chronic hemodialysis
renal replacement therapy
chronic renal failure
  • 124 views
  • 26 Feb, 2022
  • 1 location
Therapeutic Hepatitis C Virus Vaccine

GC002 is a Phase I trial to evaluate the safety and the immune responses of a lentiviral based HCV immunotherapy (HCVax) in chronic HCV patients.

  • 5 views
  • 06 Oct, 2021
  • 1 location
Treatment of Chronic Hepatitis C During Pregnancy With Sofosbuvir/Velpatasvir

A single-arm, single-center, open label Phase 1 study of a 12-week course of Sofosbuvir (SOF)/Velpatasvir (VEL) in 10 HCV-infected pregnant women 1 that will evaluate the plasma pharmacokinetic parameters of SOF/VEL administered during pregnancy and compare them to those of a historical cohort of nonpregnant women.

chronic hepatitis
hepatitis b
velpatasvir
sofosbuvir
  • 2 views
  • 12 Sep, 2021
  • 1 location