Found 30 clinical trials
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Phase 4 trial
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Accepting pediatric ages
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Accepting adults
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For females only
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Currently Recruiting
Do You Have Osteoporosis?
Do You Have Osteoporosis?
- 1122 views
- 08 Nov, 2020
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ-73763989 JNJ-56136379 Nucleos(t)Ide Analogs and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
The purpose of this study is to evaluate the efficacy in terms of hepatitis B surface antigen (HBsAg) levels of the study intervention (that is, JNJ-73763989 + JNJ-56136379 + nucleos[t]ide
- 0 views
- 24 Feb, 2021
- 11 locations
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Phase 4 trial
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Accepting adults
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An interventional trial
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For all genders
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Currently Recruiting
The Clinical Cure Project of Chronic Hepatitis B in China
nucleot(s)ide analogues(NAs) for some period can achieve higher hepatitis B surface antigen(HBsAg) clearance rate(which is called clinical cure or functional cure) by using pegylated interferon. Patients
- 6 views
- 24 Jan, 2021
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ-73763989 + JNJ-56136379 + Nucleos(t)Ide Analog (NA) Regimen With or Without Pegylated Interferon Alpha-2a (PegIFN- 2a) in Treatment-Naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection and Normal Alanine Aminotransferase (ALT)
The purpose of this study is to evaluate the efficacy of a treatment regimen of JNJ-73763989 + JNJ-56136379 + nucleos(t)ide analog (NA) with or without pegylated interferon alpha-2a (PegIFN-2a).
- 0 views
- 30 Jan, 2021
- 50 locations
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Multi-country trial
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Phase 2 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection
The purpose of this study is to evaluate the efficacy of 48-week study intervention with JNJ-73763989+JNJ-56136379+nucleos(t)ide analog (NA) regimen compared to NA alone assessed by HBsAg levels. This study is part of HepB Wings Platform Trial (PLATFORMPAHPB2001).
- 6 views
- 01 Mar, 2020
- 32 locations
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)
A study to evaluate the antiviral effects, immunogenicity, and safety of HepTcell in treatment-naive patients with inactive Chronic Hepatitis B (CHB) and low Hepatitis B surface antigen (HBsAg
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Phase 1 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study to Evaluate the Reactogenicity Safety Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' HBV (Hepatitis B Virus) Viral Vector Vaccines and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection.
A First-Time-In-Human study on GSK's therapeutic vaccines to evaluate the reactogenicity, safety, immunogenicity and efficacy on reduction of serum HBV surface antigen in HBV suppressed subjects
- 16 views
- 24 Jan, 2021
- 13 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection
PD1 blockade has been approved as salvage therapy for advanced hepatocellular carcinoma (HCC). Although there is not solid evidence that PD1 blockade would induce hepatitis B virus (HBV) reactivation, previous clinical trials of PD1 blockade required enrolled patients to receive anti-HBV medications and control the viral load to be under …
- 0 views
- 27 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting pediatric ages
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Combination Treatment of NAs and Peg IFN -2b for Hepatitis B Related Compensatory Cirrhosis Patients
The study aims to demonstrate that whether treatment of nucleoside acidanalogues (NAs) plus pegylated interferon (Peg IFN) -2b for those NAs treated, low level of HBsAg, hepatitis B related compensatory cirrhosis patients will result in higher HBsAg clearance rate and reduce the risk of liver cancer. The investigators plan to …
- 0 views
- 23 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
This is a Phase 1 dose-escalation study to evaluate the safety and tolerability of combination treatment of AZD5363 + Olaparib + Durvalumab and to determine the RP2D in patients with advanced or metastatic solid tumor malignancies. The purpose of this trial is to determine if combination treatment of drugs, Olaparib, …
- 0 views
- 22 Jan, 2021
- 1 location