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Found 8 clinical trials
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A Study of JNJ-73763989 Pegylated Interferon Alpha-2a Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

The purpose of this study is to evaluate the efficacy of a treatment regimen of JNJ-73763989 + pegylated interferon alpha-2a (PegIFN-alpha-2a) + nucleos(t)ide analog (NA).

  • 0 views
  • 29 Nov, 2021
  • 59 locations
None
Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection

The primary objective of this study is to compare the safety and efficacy of HS-10234 versus tenofovir disoproxil fumarate (TDF) in treatment-naive and treatment-experienced adults with chronic hepatitis B virus (HBV) infection.

  • 6 views
  • 22 Jan, 2021
  • 1 location
None
Study of the Safety Tolerability Pharmacokinetic and Pharmacodynamic Characteristics of PA1010 in HBV Patients

The primary objective of this study is to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of multiple ascending dose (MAD) of PA1010 tablets in Chinese adults with Chronic Hepatitis B.

  • 0 views
  • 22 Oct, 2021
  • 3 locations
None
Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis B

Although the best treatment choice for chronic hepatitis B is not clarified yet, certain therapeutic concepts could be derived from the experience of treating patients with chronic hepatitis C or human immunodeficiency virus (HIV) infection. A major advancement in treating hepatitis C or HIV infection has been the development of …

neutrophil count
chronic hepatitis
hepatitis b antigen
HIV Infection
lamivudine
  • 21 views
  • 07 Nov, 2020
None
A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B

GSK3228836 in participants with hepatitis B virus e-antigen (HBeAg)-negative CHB on stable nucleos(t)ide therapy using repeat fine needle aspirations of the liver for intrahepatic immunophenotyping. It will

hepatitis
  • 0 views
  • 29 Jul, 2021
  • 4 locations
None
Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B

Background Hepatitis B is a viral infection of the liver. When the immune system tries to clear hepatitis B, it damages the liver. Eventually, the immune system gets exhausted fighting the virus. Researchers want to see if giving large doses of an antibody (HBIg) with the drug peginterferon will boost …

chronic hepatitis
immune globulin
hepatitis b antigen
peginterferon
hepatitis b e antigen
  • 62 views
  • 28 Oct, 2021
  • 1 location
None
Predictive Model for Prognosis of Chronic HBV Infection Mothers

autoimmune diseases and immune-mediated infections. In the postpartum period. ALT ares have been reported in 20%-60% of untreated women and were more likely to occur in hepatitis B e antigen (HBeAg)-positive

  • 0 views
  • 29 Aug, 2021
  • 1 location
None
Observational Study of Persons With Hepatitis B Virus Infection in North America

Background Chronic hepatitis B virus infection is a leading cause of morbidity and mortality from end stage liver disease and liver cancer. Although significant progress has been made recently in hepatitis B therapy, current knowledge about how to manage the infection is limited because most treatment trials involve 1 to …

  • 19 views
  • 08 Nov, 2020
  • 1 location