Found 1311 clinical trials
A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Select Advanced Solid Tumors
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors
- 0 views
- 28 Oct, 2022
- 13 locations
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors
This is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary clinical efficacy of INCB106385 when given as monotherapy or in combination with INCMGA00012 in participants with selected CD8 T-cell-positive advanced solid tumors including SCCHN, NSCLC, ovarian cancer, CRPC, TNBC, bladder …
- 46 views
- 11 Jul, 2022
- 19 locations
TREATMENT OF LIVER FIBROSIS IN ADULTS WITH NONALCOHOLIC STEATOHEPATITIS (NASH)
NASH IS LIVER INFLAMMATION AND DAMAGE CAUSED BY A BUILDUP OF FAT IN THE LIVER.
- 142 views
- 03 Oct, 2019
- 1 location
Response to the HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Naive or Receiving Bruton s-tyrosine Kinase Inhibitor (BTK-I) Therapy
systems are weakened. Hepatitis B is a virus that can be transmitted when body fluids from an infected person enter the body of an uninfected person. This virus can be dangerous for people with leukemia and
- 67 views
- 09 Apr, 2019
- 1 location
A Phase III, randomized, double-blind, placebo-controlled trial in patients with Ankylosing Spondylitis (AS).
A Phase III, randomized, double-blind, placebo-controlled trial in patients with Ankylosing Spondylitis (AS).
- 1640 views
- 08 Nov, 2020
- 1 location
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)
A Phase 3, Multicenter, Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Subcutaneous Investigational Product in Patients With Systemic Lupus Erythematosus (SLE)
- 974 views
- 08 Nov, 2020
- 1 location
Alzheimer's Disease Research Center Clinic/Research Core
This study is interested to observe normal aging in the brain. This study asks: How does the brain change during normal aging? This study is looking for: Older people who are cognitively normal and live near Lexington, Kentucky.
- 128 views
- 25 Feb, 2022
- 1 location
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
- 184 views
- 25 Mar, 2021
- 1 location
Migraine Study for Men or Women ages 18 to 65 Currently Using Triptans. (e.g., Almotriptan/Axert; Frovatriptan/Frova; Rizatriptan/Maxalt; Sumatriptan/Imitrex; Zolmitriptan/Zomig)
Migraine Study for Men or Women ages 18 to 65 Currently Using Triptans. (e.g., Almotriptan/Axert; Frovatriptan/Frova; Rizatriptan/Maxalt; Sumatriptan/Imitrex; Zolmitriptan/Zomig)
- 406 views
- 08 Nov, 2020
- 1 location
A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease
A Phase Ii, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Ro4602522 Added To The Background Therapy Of The Acetylcholinesterase Inhibitors Donepezil Or Rivastigmine In Patients With Moderate Severity Alzheimer's Disease
- 174 views
- 25 Mar, 2021
- 1 location