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Found 192 clinical trials
BCG Vaccine in Reducing Morbidity and Mortality in Elderly Individuals in COVID-19 Hotspots

Rationale: SARS-CoV2 viral infection is spreading rapidly throughout the world and in India the epidemic poses a major threat to the public health system. Elderly individuals, especially those with diabetes, hypertension, other chronic diseases are at high risk of mortality. Strategies to protect these individuals are desperately needed to safeguard …

bcg vaccine
cancer
SARS
respiratory tract infection
antiviral drugs
  • 141 views
  • 24 Jan, 2021
  • 1 location
Rivaroxaban or Aspirin for Biological Aortic Prosthesis

Aortic valve replacement with a biological prosthesis is the most common valve surgery performed with about 1000 operations performed in Denmark each year. Further, the introduction of percutaneous stent valves will increase these types of replacements in the years to come. A biological valve is a foreign body prone to …

rivaroxaban
stroke
aspirin
myocardial infarction
warfarin
  • 0 views
  • 22 Jan, 2021
  • 3 locations
The Swedish BioFINDER 2 Study

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

major neurocognitive disorder
neurodegenerative disorder
cognitive impairment
screening procedures
alzheimer's disease
  • 165 views
  • 22 Jan, 2021
  • 2 locations
Full Dose Heparin Vs. Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients

The aim of this study is to test the hypothesis that prophylaxis of severe COVID-19 patients with treatment dose LMWH leads to better thromboembolic-free outcomes and associated complications during hospitalization than prophylaxis with institutional standard of care with prophylactic to intermediate-doses of UFH or LMWH

nasopharyngeal swab
enoxaparin
covid-19
  • 104 views
  • 28 Jan, 2021
  • 6 locations
Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients with

global aphasia
angiography
paresis
anesthesia
subarachnoid hemorrhage
  • 19 views
  • 17 Feb, 2021
  • 8 locations
Heparin Prophylaxis Dosing for Antepartum Hospitalizations (HEPDOSE)

This study is a randomized control trial to compare gestational age-based dosing with standard dosing of unfractionated heparin for thromboprophylaxis of hospitalized antepartum patients. The

  • 0 views
  • 02 Feb, 2021
  • 1 location
OPG and RANKL Plasma Level After Administration of Unfractionated Heparin (UFH) and Low-Molecular-Weight Heparin (LMWH) in Hemodialysis

A randomised, prospective, cross over study will be done to determine whether the anticoagulation therapy with UFH or LMWH used for hemodialysis sessions modifies osteoprotegerin and RANKL plasma levels.

heparin
  • 9 views
  • 07 Nov, 2020
  • 1 location
Nebulised Heparin in Patients With Severe COVID-19

The Can nebulised HepArin Reduce morTality and time to Extubation in Patients with COVID-19 Requiring mechanical ventilation Meta-Trial (CHARTER-MT) is a prospective collaborative individual

  • 0 views
  • 30 Jan, 2021
  • 1 location
Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19

To evaluate the safety and efficacy of the use of inhalational heparin in patients with pulmonary compromise / pneumonia / SARS associated with COVID-19, laboratory with marked inflammation

chest x-ray
pneumonia
enoxaparin
covid-19
SARS
  • 0 views
  • 25 Jan, 2021
  • 1 location
Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury

The investigators present a randomised open label phase Ib/IIa trial of nebulised unfractionated heparin to evaluate the effect of nebulised unfractionated heparin on the procoagulant response

  • 0 views
  • 19 Feb, 2021
  • 1 location