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Found 198 clinical trials
Li-Hep vs. Non-Li-Hep Coated Transfer Device

This study is a prospective, diagnostic, cohort study within the standard care of acute coronary syndrome (ACS) patients. It compares the analytical performance of Siemens point-of-care high sensitive troponin I testing in venous, plasma and capillary sample types. The investigators hypothesize that there is a good correlation between the Siemens …

chest pain
stemi
acute coronary syndrome
angiography
troponin
  • 0 views
  • 25 Jan, 2021
  • 1 location
PET-FDG in Myocarditis

This study evaluates the diagnostic performance of 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) with rest perfusion imaging for the diagnosis of myocarditis. Patients with clinical suspicion of myocarditis will be recruited and undergo a rest myocardial perfusion scan and a FDG PET/CT scan following a myocardial suppression protocol.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Extracorporeal Cytokine Removal in Patients With Septic Shock in an Adult Intensive Care Unit

Goals Primary: compare changes in norepinephrine requirements before and after hemoperfusion (HP) treatment. Secondary: demonstrate the decrease in levels of IL-6 , assess the total and individual change of SEQUENTIAL ORGAN FAILURE ASSESSMENT (SOFA), establish the resolution of shock , clearance of lactate , and mortality at discharge from INTENSIVE …

procalcitonin
norepinephrine
renal replacement
lactic acid
organ failure
  • 0 views
  • 23 Jan, 2021
  • 1 location
Prognostic Value of Lung Ultrasound in Predicting Intensive Care Unit Length of Stay in Adult Cardiac Surgery

Being easy, bedside, non-expensive, noninvasive and radiation free, there has been a growing interest in the implementation of lung ultrasound in critical care management in the last decade, cardiac surgery was not an exception in both adult and pediatric surgeries Many predictors for open heart surgery outcomes have been studied …

bypass graft
heart surgery
sternotomy
cardiopulmonary bypass
  • 0 views
  • 26 Jan, 2021
  • 1 location
Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Patients

Observational study Primary Objective: To study whether ECMO alters the PK of anti-infectives including voriconazole, posaconazole and caspofungin in critically ill patients on ECMO Secondary Objectives: Develop Population PK models of anti-infectives, including voriconazole, posaconazole and caspofungin in critically ill patients on ECMO Develop Physiological-Based PK (PBPK) model of anti-infectives, …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Prevention and Prophylaxis of Cancer Associated Thrombosis in High Risk Oncology Patients

Prevention and Prophylaxis (Thromboprophylaxis - ACT) of Cancer Associated Thrombosis (CAT) in High Risk Oncology Patients: ACT4CAT.

  • 0 views
  • 17 Feb, 2021
  • 1 location
Coagulation and Vitamin K in Head and Neck Microvascular Free Flap Surgery

For patients with large head and neck tumors the recommended treatment, in many cases, is a combination of extensive surgery and postoperative radiotherapy. The surgical procedure involves resection of the tumor and reconstruction with a so called microvascular free flap, i.e. tissue transferred from for instance the arm or leg …

  • 0 views
  • 29 Jan, 2021
  • 1 location
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors

SUMMARY Background: Improvements in the management and prevention of obstetric haemorrhage and sepsis, in addition to magnesium sulphate for preeclampsia have led to significant reduction in global maternal mortality rates; thus leaving increasing number of survivors of preeclampsia than previously. Preeclampsia is associated with inflammatory changes that alter vascular integrity …

hypertension
stroke
  • 7 views
  • 24 Jan, 2021
  • 1 location
Feasibility of Novel Clinical Trial Infrastructure Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH)

Prospective, open-label, single centre, observational study to evaluate the safety and feasibility of using pulmonary artery pressure (PAP) monitors and wearable activity monitors in patients with pulmonary hypertension (PH).

heart failure
body mass index
  • 4 views
  • 24 Jan, 2021
  • 1 location
DNA Methylation Analysis in Acute Coronary Syndrome and Atrial Fibrillation: DIANA Clinical Trial

Although epigenetics has been identified as one of the most relevant pathophysiological components in the development of cardiovascular diseases, there is still considerable difficulty in finding markers of epigenetic damage useful in clinical practice. Moreover, these markers could be useful to predict the onset and severity of disease as well …

fibrillation
myocardial infarction
stemi
acute coronary syndrome
unstable angina
  • 0 views
  • 26 Jan, 2021
  • 1 location