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Found 87 clinical trials
Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres 1 mg

The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal pathogens and overall bacterial load. A randomized controlled clinical trial of a control (SRP) group and an experimental (SRP with …

  • 26 Jan, 2021
  • 1 location
Overcoming Barriers and Obstacles to Adopting Diabetes Devices (ONBOARD) RCT

This study is a comprehensive, multicomponent behavioral intervention package (ONBOARD; OvercomiNg Barriers & Obstacles to Adopting Diabetes Devices). ONBOARD will provide adults with T1D the skills to maximize benefit and minimize daily interference from barriers associated with Continuous Glucose Monitoring (CGM) and increase readiness for closed loop.

  • 07 Mar, 2021
  • 1 location
Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease

This is a treatment study to determine if reducing the body's iron stores by blood donation will improve diabetes control and other problems associated with diabetes such as fatty liver disease.

glucose intolerance
fatty liver
liver disease
  • 27 Jan, 2021
  • 2 locations
Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults

The overall objectives are to: Assess mechanisms underlying HIIT-induced improvements in insulin resistance at the whole-body, tissue, and cellular levels. Systematically compare different HIIT regimens to help identify effective "doses" of HIIT that may be optimal for improving metabolic health in obese adults. Assess the ability/willingness of obese subjects to …

insulin resistance
body mass index
glucose concentration
  • 08 Mar, 2021
  • 1 location
The Effect of Blood Flow Restriction Training on Glycemic Control Among Type 2 Diabetes Patients

Blood flow restriction training (BFRT) combined with resistance or aerobic exercise has been shown to improve the glucose uptake in humans. In addition, BFRT represents a low-load, alternative exercise program for type 2 diabetes patients who often have reduced physical fitness. However, it is not clear to what extent could …

hemoglobin a1c
oral glucose tolerance test
glucose tolerance test
fasting blood glucose
  • 16 Jul, 2021
  • 1 location
The Effect of Dapagliflozin on Ultrafiltration Among Peritoneal Dialysis Patients

Patients with average or high average peritoneal glucose transport status be included in the study as mentioned in the inclusion and exclusion criteria. The change in peritoneal glucose transport will be evaluated before and after one month treatment with 10 mg of Dapagliflozin. Peritoneal Equilibration Test (PET) test for patients …

  • 19 Jun, 2021
  • 1 location
Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis

This study will evaluate the effect of probiotics, a beneficial intestinal bacteria supplement, if it will cause improvement of the non-alcoholic fatty liver disease (NAFLD) and or non-alcoholic steatohepatitis (NASH- an inflammation with concurrent fatty accumulation of the liver) as measured by transient elastography - an ultrasound of the liver …

  • 24 Apr, 2021
  • 1 location
Comparison of Glucovance to Insulin for Diabetes During Pregnancy

Pregnant women with gestational or Type 2 diabetes who require medication are placed in one of two groups: Insulin injections or Glucovance (oral administration). Blood glucose is checked 5 times per day, and medication adjusted by perinatologist according to glucose levels. The hypothesis is that patients will have similar or …

type 2 diabetes mellitus
  • 07 Nov, 2020
  • 1 location
My Dose Coach and Connected Ecosystem

The purpose of this research study is to evaluate an electronic application (app) designed to help people with type 2 diabetes (T2DM) adjust their insulin doses. The app is called My Dose Coach. This research study is being done in 2 phases. Specifically in Phase 1, the study is assessing …

  • 21 Apr, 2021
  • 1 location
Dapagliflozin In Alzheimer's Disease

This is a pilot randomized controlled trial in individuals with probable Alzheimer's disease testing the effects of 10 mg dapagliflozin, taken daily for 12 weeks, on cerebral n-acetyl aspartate (NAA) levels using magnetic resonance spectroscopy (MRS). The investigators will also examine the safety and tolerability of dapagliflozin and explore the …

body mass index
alzheimer's disease
mini-mental state examination
  • 26 Jan, 2021
  • 1 location