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Found 32 clinical trials
Genotype-Phenotype Correlations in Patients With Alport Syndrome

Alport syndrome (AS) is caused by pathogenic variants in the type IV collagen genes COL4A3, COL4A4, and COL4A5. This study aims to enroll families and patients with a history of renal hematuria

  • 11 Jul, 2021
  • 1 location
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients (NEXUS AP CT)

, hip pain, hematuria, hypotension, tachycardia, low or falling hematocrit, intoxication, altered sensorium, distracting injury, positive FAST imaging, dangerous mechanism, abnormal x-ray imaging) will

Accepts healthy volunteers
  • 13 Oct, 2022
Feasibility and Efficacy of Upright MP - MRI for Prostate Cancer Screening

This is an investigator initiated study to test the efficacy of an upright MRI (Magnetic Resonance Imaging) for the screening of prostate cancer. The purpose of this study is to compare Upright MRI as a technique to PSA (Prostate Specific Antigen) and current MRI imaging. It will take place at …

prostate cancer screening
digital rectal exam
prostate specific antigen
digital rectal examination
  • 11 Oct, 2022
  • 1 location
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID) (RENAL AID)

A central goal of this data repository is to collect data from a large population of subjects with a variety of renal disease states. Cohorts will include subjects with diabetes, inflammatory/autoimmune and transplant related renal conditions. Additionally, the repository will have the capacity to store biospecimens and electronic data in …

type 2 diabetes
biopsy tissue
biological factors
kidney biopsy
  • 11 Oct, 2022
  • 1 location
Investigation on a Dynamic Cohort of Italian Patients With Active ITP (ITP0918)

The objective of the study is to produce a dynamic picture of the adult ITP natural history and management in Italy by collecting standardized information retrospective and prospective data of patients in active management through a nation-wide registry.

  • 04 Oct, 2022
  • 26 locations
  • 09 Apr, 2022
  • 4 locations
European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

The hereditary type IV collagen disease Alport syndrome inevitably leads to end-stage renal disease. Currently there are no therapies known to improve outcome. Our non-interventional, observational study investigates, if medications such as ACE-inhibitors can (1) delay time to dialysis and (2) improve life-expectancy within three generations of Alport-families in Europe.

Accepts healthy volunteers
  • 05 Jun, 2022
  • 1 location
Prospective Evaluation of Blunt Renal Injury in Children

, operation, subsequent hypertension and clearance of hematuria. The specific aim of the study is to prospectively collect the clinical data of these children to validate our hospital management and to define

  • 22 Mar, 2022
  • 1 location
Study of the Effects of Anticoagulant Interruption Covered by Percutaneous Left Atrial Occlusion in Patients With Chronic Atrial Fibrillation and Radiation Cystitis at Risk of Bleeding

prostate cancer treatment is radiotherapy. The prevalence of haematuric radiation cystitis is 4-5% (about 800 patients). One of the complications of radiation cystitis is persistent hematuria. There

  • 22 Aug, 2021
  • 1 location
Novel mRNA-based Urine Test for Bladder Cancer in Spinal Cord Injury Individuals

advanced stage at the time of diagnosis compared to bladder cancer in the general population. Individuals with bladder cancer commonly present with hematuria and other urinary symptoms. The gold standard

bladder tumor
spinal cord
bladder cancer
  • 21 Mar, 2022
  • 1 location