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Found 5 clinical trials
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

The purpose of this Phase 3 study is to evaluate the efficacy and safety of Luspatercept compared with placebo in subjects with myeloproliferative neoplasm (MPN)-associated Myelofibrosis (MF) and anemia on concomitant Janus kinase 2 (JAK2) inhibitor therapy and who require red blood cell count (RBC) transfusions. The study is divided …

vasectomy
cancer
anemia
bilateral oophorectomy
  • 0 views
  • 02 Aug, 2021
  • 158 locations
Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury

background about neurotrophic and neuroprotective effects of this hematopoietic growth factors therapy.

  • 0 views
  • 26 Jan, 2021
MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed Platelet Engraftment

The purpose of this study is to compare the efficacy of mesenchymal stem cells (MSCs) with or without granulocyte colony-stimulating factor (G-CSF) mobilized peripheral stem cells (PBSC) in treating patients experiencing poor graft function or delayed platelet engraftment after allogeneic hematopoietic stem cell transplantation.

mobilized
allogeneic hematopoietic stem cell transplant
g-csf
cell transplantation
granulocyte colony stimulating factor
  • 17 views
  • 07 Nov, 2020
  • 1 location
Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)

The purpose of this study is to determine if AR-67 is effective in the treatment for patients with MDS.

azacitidine
decitabine
chronic myelomonocytic leukemia
hydroxyurea
leukemia
  • 30 views
  • 08 Nov, 2020
  • 1 location
Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"

Bone marrow consists of a complex hematopoietic cellular component.When the blood progenitor cells differentiate to mature cells, they will exit unassisted to peripheral blood. On the other hand, the immature cells trapped by marrow-blood barrier. However, malignant transformation of the hematopoietic progenitor cells in AML and CML results in a …

acute leukemia
  • 14 views
  • 07 Nov, 2020
  • 1 location