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Found 9 clinical trials
Fecal Microbiota Transplantation in aGvHD After ASCT

Acute graft-versus-host-disease (aGvHD) is a typical complication after allogeneic hematopoetic stem cell transplantation (ASCT). About 30-60% of patients after ASCT are affected by aGvHD, which

  • 0 views
  • 23 Apr, 2022
  • 1 location
A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

The purpose of this Phase 2/3 study is to evaluate efficacy and safety of the combination of selinexor and R-GDP (SR-GDP) in patients with RR DLBCL who are not intended to receive hematopoetic

  • 134 views
  • 30 May, 2022
  • 36 locations
International Study for Treatment of High Risk Childhood Relapsed ALL 2010

The main goal of this study is to improve the outcome of children and adolescents with acute lymphoblastic leukemia with high risk first relapse by optimization of treatment strategies within a large international trial and the integration of new agents.

  • 34 views
  • 05 Mar, 2022
  • 10 locations
Best Available Therapy Versus Autologous Hematopoetic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) (BEAT-MS)

This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio. …

tecfidera
teriflunomide
rituximab
MRI
aubagio
  • 418 views
  • 16 Jun, 2022
  • 16 locations
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

This is a standard of care treatment guideline for allogeneic hematopoetic stem cell transplant (HSCT) in patients with primary immune deficiencies.

melphalan
lymphoproliferative disorder
chediak-higashi syndrome
severe combined immunodeficiency
bone marrow transplant
  • 299 views
  • 29 Apr, 2022
  • 1 location
Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab

disease has relapsed after receiving allogeneic hematopoetic stem cell transplant.

lymphoid leukemia
bone marrow procedure
cancer
leukemia
myeloid leukemia
  • 11 views
  • 23 Apr, 2022
  • 1 location
MNGIE Allogeneic Hematopoietic Stem Cell Transplant Safety Study

The purpose of this study is to find out if a stem cell transplant is safe for patients with a very rare disease. The stem cell transplant is called AHSCT (for "allogeneic hematopoetic stem cell

  • 30 views
  • 23 Jan, 2021
  • 1 location
Neoadjuvant Toripalimab in Combination With Gemcitabine and Cisplatin Therapy in Local Advanced Bladder Cancer Subjects

This is a pre-surgical study involving subjects with local advanced bladder cancer, who are candidates for neoadjuvant therapy. It is a single-arm phase II portion.

measurable disease
bladder tumor
gemcitabine
radical cystectomy
carcinoma
  • 0 views
  • 21 Mar, 2022
  • 1 location
Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantation

This research study is studying a drug called obinutuzumab as a means of preventing chronic Graft vs. Host Disease (cGVHD).

neutrophil count
cell transplantation
leukemia
lymphoma
ct scan
  • 10 views
  • 07 Apr, 2022
  • 5 locations